文章摘要
徐凌云,赵文彬,刁连东,吴桃林,张学年,周克捷,王理兴.环境水中脊髓灰质炎病毒二年循环动态研究[J].中华流行病学杂志,1996,17(4):236-238
环境水中脊髓灰质炎病毒二年循环动态研究
A Study of the Cyclic Development of Poliomylitic Virus in Pond Foul Water during A Two-Year Span
收稿日期:1996-01-05  出版日期:2021-05-13
DOI:
中文关键词: 脊髓灰质炎病毒  疫苗株
英文关键词: Polio virus  Strain of sabin
基金项目:
作者单位
徐凌云 江苏省卫生防疫站 南京 210009 
赵文彬 连云港市卫生防疫站 
刁连东 江苏省卫生防疫站 南京 210009 
吴桃林 连云港市卫生防疫站 
张学年 连云港市卫生防疫站 
周克捷 连云港市卫生防疫站 
王理兴 连云港市卫生防疫站 
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中文摘要:
      1993~1995年作者在连云港市选近三年曾有脊髓灰质炎病例的乡(镇),采用氯化钠-三氯化铝沉淀法对河塘污水中脊髓灰质炎病毒(PV)循环动态进行研究。发现:在连续二年的各个季节采集的水样中均能分离到致Hep-2细胞病变的病毒(57.95%),经鉴定:21株为PV(23.86%),其中PV Ⅰ 18株、PV Ⅱ 1株、PV Ⅲ 2株,另30株(34.09%)为非脊灰肠道病毒(NPEV)。鉴于我国目前脊灰流行毒株主要为PV Ⅰ,经RT-PCR试验,所分离的PV Ⅰ均为疫苗(Sabin)相关株,初步表明调查地区的外环境的PV已被疫苗相关株所取代。
英文摘要:
      A study on polio virus in pond foul water of town and counties in Lian Yun Gang city which had a reported case of polio. Foul water was examined by 1% NaCl-AlCl3 precipitated method quarterly during 1993-1995, to observe the cyclic development of the virus. Results showed that the isolation rate of polio virus was 57.95% with 21 strains of 18 PV Ⅰ, 1 PV Ⅱ and 2 PV Ⅲ and 30 strains of NPEV (34.09%). In view of PV Ⅰ as main epidemic strain in our coun try, and related strains to sabin was confirmed using RT-PCR. The above data suggested that polio virus in the pond water had been replaced by relative strains of sabin.
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