文章摘要
周家仪,沈靖,邵亚农,谈永飞,姚才良,徐希平.脑梗塞危险因素的交互作用分析[J].中华流行病学杂志,1997,18(5):279-281
脑梗塞危险因素的交互作用分析
Analysis on the Interaction Among Agents in Arteriosclerotic Cerebral Infarction
收稿日期:1997-06-30  出版日期:2021-06-09
DOI:
中文关键词: 脑梗塞;危险因素;交互作用
英文关键词: Arteriosclerotic ceerbral infarction;Etiology;Interaction
基金项目:
作者单位
周家仪 南京医科大学公共卫生学院 210029 
沈靖 南京医科大学公共卫生学院 210029 
邵亚农 宜兴市人民医院康夏科 
谈永飞 宜兴市人民医院康夏科 
姚才良 南京医科大学公共卫生学院 210029 
徐希平 哈佛大学公共卫生学院 
摘要点击次数: 120
全文下载次数: 39
中文摘要:
      本研究通过1:1配比病例对照研究,对脑梗塞危险因索之间的交互作用进行了分析。结果表明:脑梗塞的主要危险因素为TG、Lp (a)和BMI,而HDL-C是唯一的保护因素,Lp (a)与BMI进行分级后,仍可看出对脑梗塞的剂量效应关系,考虑到各因素间较强的相关关系,进一步对入选因素进行了对数线性模型拟合,结果显示:是否患脑梗塞与TC、TG、HDL-C、Lp (a)之间的交互作用显著,TC、TG、HDL-C和LDL-C之间两两均有交互作用,说明血脂因素之间的交互作用是确实存在的,但在何种水平上的交互作用最大,还需进一步的定量分析。
英文摘要:
      An 1:1 matched case-control study including 105 arteriosclerotic cerebral infarction cases and 105 controls was carried out to estimate the etiologic interaction, in Yi-xing city, March 1997. Results showed that the major risk factors were high levels of serum TG, Lp(a) and BMI while serum level of HDL-C was the only protective factor. When several levels were divided on Lp(a) and BMI, a significantly dose response relation was found. Considering the correlation among serum concentration of lipids, we analysed the interaction of different factors, using Log-Linear models. Results showed that there were significant interactions between arteriosclerotic cerebral infarction and TC, TG, HDL-C and Lp(a). There were also interactions between TC, TG, HDL-C and LDL-C. However, the strongest interaction is expected to happen at what level remains further investigations.
查看全文   Html全文     查看/发表评论  下载PDF阅读器
关闭