| 周家仪,沈靖,邵亚农,谈永飞,姚才良,徐希平.脑梗塞危险因素的交互作用分析[J].中华流行病学杂志,1997,18(5):279-281 |
| 脑梗塞危险因素的交互作用分析 |
| Analysis on the Interaction Among Agents in Arteriosclerotic Cerebral Infarction |
| 收稿日期:1997-06-30 出版日期:2021-06-09 |
| DOI： |
| 中文关键词: 脑梗塞 危险因素 交互作用 |
| 英文关键词: Arteriosclerotic ceerbral infarction Etiology Interaction |
| 基金项目: |
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| 摘要点击次数: 1082 |
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| 中文摘要: |
| 本研究通过1：1配比病例对照研究，对脑梗塞危险因索之间的交互作用进行了分析。结果表明：脑梗塞的主要危险因素为TG、Lp （a）和BMI，而HDL-C是唯一的保护因素，Lp （a）与BMI进行分级后，仍可看出对脑梗塞的剂量效应关系，考虑到各因素间较强的相关关系，进一步对入选因素进行了对数线性模型拟合，结果显示：是否患脑梗塞与TC、TG、HDL-C、Lp （a）之间的交互作用显著，TC、TG、HDL-C和LDL-C之间两两均有交互作用，说明血脂因素之间的交互作用是确实存在的，但在何种水平上的交互作用最大，还需进一步的定量分析。 |
| 英文摘要: |
| An 1:1 matched case-control study including 105 arteriosclerotic cerebral infarction cases and 105 controls was carried out to estimate the etiologic interaction, in Yi-xing city, March 1997. Results showed that the major risk factors were high levels of serum TG, Lp(a) and BMI while serum level of HDL-C was the only protective factor. When several levels were divided on Lp(a) and BMI, a significantly dose response relation was found. Considering the correlation among serum concentration of lipids, we analysed the interaction of different factors, using Log-Linear models. Results showed that there were significant interactions between arteriosclerotic cerebral infarction and TC, TG, HDL-C and Lp(a). There were also interactions between TC, TG, HDL-C and LDL-C. However, the strongest interaction is expected to happen at what level remains further investigations. |
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