文章摘要
范若兰,郑素华,吴兆苏,曹丽华,凌颖.肺癌患者与发病前心理社会因素关系的病例对照研究[J].中华流行病学杂志,1997,18(5):289-292
肺癌患者与发病前心理社会因素关系的病例对照研究
Study on the Relationship between Lung Cancer at Preclinic Stage and Psycho-social Factor-A Case-Control Study
收稿日期:1996-10-20  出版日期:2021-06-09
DOI:
中文关键词: 肺癌  心理社会因素  比值比  对比研究
英文关键词: Lung cancer  Stage and psychosocial factor  Odds ratio  Comparative study
基金项目:
作者单位
范若兰 北京市结核病胸部肿瘤研究所 101149 
郑素华 北京市结核病胸部肿瘤研究所 101149 
吴兆苏 北京市心肺血管医疗研究中心 
曹丽华 北京市结核病胸部肿瘤研究所 101149 
凌颖 北京市结核病胸部肿瘤研究所 101149 
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中文摘要:
      本文病例组为原发性肺癌309例(男193,女116),人群对照组1 231例(男768,女463)。在SINO-MONICA (WHO)项目的监测人群中进行病例对照研究,试图探索肺癌患者与发病前6项心理社会因素的关系。结果有3项与肺癌呈阳性关联。即情绪不能自我调节(OR=1.82,P<0.01),人际关系包括同事关系差(OR:1.37,P<0.05)、上下级关系差(OR=1.55,P<0.01)和精神长期受压抑(OR=4.14,P<0.01)。如将精神长期受压抑作为危险因素,按其人群暴露率8.8%计算,其人群归因危险度百分数(PAR%)为21.6%。
英文摘要:
      A case-control study of primary lung cancer patients including 309 case (male 193, female 116) and 1231 controls (male 768, female 463) was carried out in the monitored population for SINO-MONICA Project (WHO) during 1990-1993. This was a population based case-control study involved 0.75 million population in order to detect the relationship between lung cancer at preclinic stage and 6 psychosocial factors. There were 3 factors positively associated with lung cancer. They were 1) burst of "emotion and could not be controlled" (OR 1.82 P<0.01), 2) "poor working circumstances" including poor relationship with colleagues (OR 1.37 P<0.05) and superiors (OR 1.55 P<0.01) and the"depressive feeling for a long time" (OR 4.14 P<0.01). when we considered "long standing depressive feeling" as a risk factor for lung cancer and calculated by an exposure rate of 8.8%, the population attributable risk percent (PAR%) would be 21.6% (male 18.7%, female 26.4%). Our findings suggested that the relationship between lung cancer at preclinic stage and psycho-social factor did exist.
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