文章摘要
倪进发,阚晓宏,毕鹏,孙业桓,章秋霞,张庶民,程慧,黄守凯.丙型肝炎病毒感染后慢性转化率的流行病学研究[J].中华流行病学杂志,1998,(3):144-146
丙型肝炎病毒感染后慢性转化率的流行病学研究
An Epidemiological Study on the Rate of Becoming Chronic in HCV Infection
收稿日期:1997-10-31  出版日期:2014-09-16
DOI:
中文关键词: 丙型肝炎;慢性转化率
英文关键词: Hepatitis C;Chronic rate
基金项目:安徽省自然科学基金
作者单位
倪进发 安徽医科大学流行病学教研室, 合肥 230032 
阚晓宏 安徽医科大学流行病学教研室, 合肥 230032 
毕鹏 安徽医科大学流行病学教研室, 合肥 230032 
孙业桓 安徽医科大学流行病学教研室, 合肥 230032 
章秋霞 安徽省立医院传染科 
张庶民 中国药品生物制品检定所疫苗二室 
程慧 安徽医科大学流行病学教研室, 合肥 230032 
黄守凯 安徽医科大学流行病学教研室, 合肥 230032 
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中文摘要:
      笔者选择1992~1996年间,安徽某乡“职业”供血员和2所省级医院住院病人中,抗-HCV(+)和/或HCV RNA(+)者为调查对象。追访了他们HCV感染及其后的有关重要临床诊治和流行病学信息,同时调查了感染者的现况及相关实验室指标检测,描述了供血员人群丙型肝炎病毒感染后慢性转化率变化趋势。结果HCV感染6个月后慢性转化率为55.93%,1~4年慢性转化率依次为50%、48.54%、46.47%和46.43%。表明其感染后慢性转化率一直持续高水平,下降缓慢,尤其2年后基本稳定在46%~48%,远高于乙型肝炎5%~10%的慢性转化率。
英文摘要:
      Anti-HCV(+) and/or HCV RNA(+) were chosen for study on patients admitted to two provincial hospitals and “professional” blood donors in one of the areas in Anhui province in 1992-1996.Clinical diagnosis,treatment and epidemiology on HCV infection were retrospectively reviewed and in the meantime their present condition together with experimental data were studied;Chronic tendency on HCV infection of blood donors was described.Results showed that the rates of duration on becoming chronic for HCV infection were:six month later-55.93%,one year-50%,two-years-48.54%,three years-46.47% and four years-46.43%.Rate of becoming chronic after HCV infection was continuously in high level,then slowly decreasing, to 46%-48% in two years,still much higher than hepatitis B which had a rate of 5%-10% becoming chronic.
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