文章摘要
黄亚玲,李建新,向幼华,曾靖.急性菌痢治疗方案的卫生经济学研究[J].中华流行病学杂志,1998,(3):154-156
急性菌痢治疗方案的卫生经济学研究
Study on the Cost-effectiveness of Therapeutic Scheme of Acute Bacillary Dysentery
收稿日期:1997-12-15  出版日期:2014-09-16
DOI:
中文关键词: 菌痢;卫生经济学;氨基糖甙类;头孢三代类
英文关键词: Bacillary dysentery;Hygienic economics;Aminoglycoside;The 3rd generation of cephalosporin
基金项目:
作者单位
黄亚玲 同济医科大学第一临床学院, 湖北 武汉 430022 
李建新 武汉市儿童医院 
向幼华 同济医科大学第一临床学院, 湖北 武汉 430022 
曾靖 武汉市儿童医院 
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中文摘要:
      笔者通过应用氨基糖甙类及头孢三代类抗生素治疗急性细菌性痢疾的前瞻性临床研究,体外药物敏感试验的实验研究及药物治疗成本的统计学研究,发现两类抗生素的临床疗效及体外敏感率无差异(P>0.05),而其治疗成本(用每天每公斤体重多少元人民币表示)却差异有显著性。三代头孢类平均治疗成本是氨基糖甙类的44.85倍,最大成本复达新是最小成本庆大霉素的364倍。采用成本最小分析法进行卫生经济学评价认为治疗菌痢不宜首选三代头孢类抗生素。
英文摘要:
      A prospective study on the costs of acute bacillary dysentery treatment with antibiotics of aminoglycoside and the 3rd generation of cephalosporin,along with drug sensitive test in vitro was carried out.The results showed that the clinical therapeutic effects and the sensitive rates to drug in vitro between the two kinds of antibiotics were not statistically different (P>0.05),but the costs of treatment with these two methods were significantly different.The therapeutic costs were calculated in Ren Ming Bi per day per kilogram body weight.The average therapeutic cost with the 3rd generation of cephalosporin was 44.85 times as that with aminoglycoside.The highest cost by Fortum was 364 times Higher than by Gentamycin.Through cost analysis,conclusion was drawn that the 3rd generation of cephalosporin should not be taken as first choice to treat a acute bacillary dysentery.
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