| 周铁群,王剑锋,邱平,李长贵,韩秀娟,殷文武,李志仁,万卓越,金艾顺,张静,黄丽娟,王开利.儿童水痘血清流行率调查及其疫苗免疫效果[J].中华流行病学杂志,1998,19(5):271-273 |
| 儿童水痘血清流行率调查及其疫苗免疫效果 |
| Investigation on Sera Prevalence Rate of Varicella and Immunogenicity of Varicella Vaccine in HealthyChildren |
| 收稿日期:1997-12-16 出版日期:2014-09-16 |
| DOI： |
| 中文关键词: 水痘 流行率 Oka水痘疫苗 免疫效果 |
| 英文关键词: Varicella Prevalence rate Oka varicella vaccine Immuner esponse |
| 基金项目: |
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| 中文摘要: |
| 为了解儿童水痘流行情况及水痘减毒活疫苗的免疫效果,采用全抗原ELISA方法对315名3～7岁儿童水痘的血清流行情况进行了调查,血清抗VZV-IgG阳性率为41.6%,且不同幼儿园中水痘流行情况有所不同,表现出明显的群体差异。同时对Oka株水痘减毒活疫苗在该人群的免疫效果进行了调查,结果表明该疫苗接种后无明显副反应,血清阳转率为85.1%。证明了减毒活疫苗有良好的安全性和有效性。 |
| 英文摘要: |
| A whole varicella virus antigen-ELISA method was used to investig ate the sera prev alence rate of var icella in 315 healthy children aged 3-7 years. Results showed that the sera positive rate of anti-VZV-I gG was 41.6%. Differ ent prevalence rates in differ ent kindergartens were noticed, character izing the differences of populations. I mmunog enicity of Oka strain attenuated varicella vaccine among children was also studied. No obvious adverse reactions were observed and the seraconversion rate was 85.1%. |
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