文章摘要
李大林,李立明.基因-环境交互作用研究方法:无对照病例研究[J].中华流行病学杂志,2002,23(4):304-307
基因-环境交互作用研究方法:无对照病例研究
A diagnosis test of stress fracture during basic training set for new military recruits
收稿日期:2001-12-04  出版日期:2014-09-18
DOI:
中文关键词: 应力性骨折;诊断试验
英文关键词: Stress fracture;Diagnosis test
基金项目:
作者单位
李大林 北京大学公共卫生学院流行病学教研室 100083 
李立明 中国疾病预防控制中心 
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中文摘要:
      目前许多对复杂性状疾病病因的遗传流行病学研究得到非常不一致的结论,没有考虑到基因-环境交互作用应该是重要原因之一。
英文摘要:
      Objective To evaluate efficacy of stress fracture (SF) during basic training for military recruits using clinical diagnosis method. Methods Two hundred and eighty eight suspected SF were checked clinically and with bone scanning as golden standard. Results Sensitivity, specificity, accuracy, positive and negative predictive value, positive and negative likelihood ratios and Youden's index of clinical diagnosis were found to be 97.5 %, 61.7 %, 91.7 %, 92.9 %, 82.9 %, 2.55, 0.04 and 0.59 respectively when calculated with cases. The agreement rate between two physicians was 81.7 % with kappa value 0.64. When calculated with position, the precious measures were 97.2 %, 84.1 %, 89.7 %, 82.0 %, 97.6 %, 6.12, 0.03, and 0.81 respectively. The agreement rate between two physicians was 94.4 % with kappa value 0.88. Conclusion Efficacy reliability and agreement of clinical diagnosis for SF seemed to be satisfactory.
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