| 余宏杰,罗会明,鲁锡荣,宋曲波,范子凡.广东省阳江某刀具厂急性亚硝酸盐中毒调查[J].中华流行病学杂志,2002,23(6):419-421 |
| 广东省阳江某刀具厂急性亚硝酸盐中毒调查 |
| Investigation on acute nitrite poisoning in Yangjiang city, Guangdong province, China |
| 收稿日期:2002-05-17 出版日期:2014-09-18 |
| DOI： |
| 中文关键词: 亚硝酸盐|中毒|饮用水|环境污染 |
| 英文关键词: Nitrite|Poisoning|Drinking water|Environmental pollution |
| 基金项目: |
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| 中文摘要: |
| 目的 揭示广东省阳江某刀具厂急性中毒事件的主要原因,探讨中毒的主要危险因素。 方法 对工厂管理人员、中毒患者、经治医生、生活用水的污染过程以及工业废水的处理、排放细节进行现况调查。采用面对面问卷调查员工的发病情况和主要暴露因素。 结果 发病36例, 罹患率为16.4%(36/220)。 饮用水集中在当天下午上班后13:00至15:30,发病高峰在15∶00左右, 潜伏期中位数为90min。 不同饮水量的工人罹患率不同, 随着饮水量的增加, 罹患率也增加, 存在比较明显的剂量反应关系 (χ2趋势 =79.115, P<0.01)。实验室检测工人饮用后的残留水亚硝酸盐含量严重超标。结论 此事件为一起饮用水被亚硝酸盐污染导致的急性中毒。当地刀具生产企业对亚硝酸盐等有毒化学品的保管使用、供水系统的设计以及工业废水处理排放后对人群健康和环境的影响值得有关部门的密切关注。 |
| 英文摘要: |
| Objective To determine the cause of acute poisoning occurred in a factory in Yangjiang city, Guang dong province. Methods In a cross-sectional study, interviews were conducted with the administratives of the factory and the local physician. A review was conducted on the water system used for industrial purposes and a separate system used by wor kers for drinking water. Treatment and discharge of industrial waste water were examined. Face-to-face interview was conducted to identify risk of exposure for illness among workers. Results A total number of 36 cases were identified in the plant and the attack rate was 16.4% ( 36/220). The incubation period (time betw een drinking polluted water and the onset of symptoms) had a median of 90 minutes ( range: 30-230 minutes). Consuming water at the factor yincreased the attack rate and a dose-response effect was identified (V2 trend=79.115,P<0.01). The nitrite content of residuals in drinking water exceeded the WHO standard ( 1 ppm ). Conclusions The accident of acute poisoning was due to drinking water contaminated with sodium nitrite. The prevention of drinking water contaminated by toxic chemicals like sodium nitrite, and the design of industrial and potable water supply system need to be carefully reviewed. Regulations should be developed and enforced to minimize the impact of industrial waste water discharges to guarantee the access to clean drinking water. |
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