龚晓红,李阳桦,刘立荣,贾蕾,邢玉兰,王玉琴.北京市青少年乙型肝炎疫苗免疫效果观察[J].中华流行病学杂志,2004,25(5):388-390 |
北京市青少年乙型肝炎疫苗免疫效果观察 |
Study on the afficaay of bepatitis B immunization among youngsters in Beijing |
收稿日期:2004-01-16 出版日期:2014-09-17 |
DOI: |
中文关键词: 乙型肝炎 疫苗 青少年 免疫 效果 |
英文关键词: Hepatitis B vaccine Callans Immune Effective |
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中文摘要: |
目的: 评价青少年接种乙型肝炎(乙肝)疫苗后的流行病学效果。方法: 收集接种人群历年的接种报告、现场调查该人群的乙肝血清学流行率以及疫苗接种情况,分析接种疫苗前、后历年来乙肝发病的疫情报告, 采用放射免疫分析法测定乙肝表面抗原(HBsAg)、抗-HBs和抗-HBc, 并与接种前期的检测结果进行比较。结果: 青少年接种乙肝疫苗后, 其乙肝发病率由接种前期的12.11/10万~16.89/10万降至1.78/10万~10.95/10万(X~2=10.71~60.45,P<0.01), HBsAg携带率由6.34%降至1.37%, 下降约80.00%(X~2=14.16,P<0.01)。结论: 青少年接种乙肝疫苗是预防和控制乙肝感染的有效手段。 |
英文摘要: |
Objective: To evaluating the epidemiological effect atter hepatitis B immunization among youngsters in Beijing. Methods: A multistage sampling method was used for data collection from immunization cards, reports on field epidemiological survey on hepatitis B virus(HBV) immunization of youngsters and the analysisi of infectious diseases. HBsAG, nti-HBs and anti-HBc levels were detected by solid phase radiommuunoassays(SPRIA). Results: The average incidence rates of hepatitis B in 10-19 years-olds prior to HBV immunization was 12.11-16.89/100000, while declined to 1.78-10.95/100000(x2=10.71-60.45, P<0.01). HBsAg carrying rate of the youngsters decrezsed from 6.34 to 1.37% (80.00%) after vaccination (x2-14.16, P<0.01). Conclusion: Hepatitis B vaccination among youngsters is an effective measure for the prevention and control of hepatitis B virus infection. |
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