急性生理学和慢性健康状态评分与急性肺损伤评分在重症SARS患者中的应用

张国强; 顾承东; 朱宇清; 王丽晔; 刘鹏

文章摘要

张国强,顾承东,朱宇清,王丽晔,刘鹏.急性生理学和慢性健康状态评分与急性肺损伤评分在重症SARS患者中的应用[J].中华流行病学杂志,2004,25(9):802-804

急性生理学和慢性健康状态评分与急性肺损伤评分在重症SARS患者中的应用

Comparison between tow methods of acute physiology and chronic health evaluation Ⅲ and acute lung injury scale to evaluate the severity and prognosis of severe acute respiratory syndrome

收稿日期: 出版日期:2014-09-15

DOI：

中文关键词: 严重急性呼吸综合征|急性生理学和慢性健康状态评分|急性肺损伤评分

英文关键词: Severe acute respiratory syndrome|Acme physiology and chronic health evaluation|Acute lung injury scale

基金项目:

作者	单位
张国强	100029 北京中日友好医院急诊科
顾承东	100029 北京中日友好医院急诊科
朱宇清	100029 北京中日友好医院急诊科
王丽晔	河北省开滦唐家庄医院
刘鹏	100029 北京中日友好医院急诊科

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中文摘要:

目的评估急性生理学和慢性健康状态评分Ⅲ(APACHE Ⅲ)和急性肺损伤(ALI)评分对严重急性呼吸综合征(SARS)的病情严重程度和预后的价值. 方法对38例重症SARS患者应用APACHE Ⅲ和ALI评分, 并对结果进行比较. 结果死亡组(14例)的APACHE Ⅲ平均分值为74.9±22.3明显高于存活组(24例)平均分值38.3±13.2(P＜0.001), APACHE Ⅲ各分段值与病死率呈正相关, APACHE Ⅲ分值≥60分, 病死率明显增高(χ²=3.886, P＜0.05); 老年组(18例)的病死率明显高于非老年组(20例)(χ²=8.660, P＜0.05); 但死亡组和存活组的ALI评分分值差异无显著性(P=0.127). 结论 APACHE Ⅲ较ALI评分更能准确地判断重症SARS患者病情严重程度和预后; 老年人重症SARS的病死率明显升高.

英文摘要:

Objective To evaluate the acute physiology and chronic health evaluation Ⅲ (APACHEⅢ)and acute lung injury(ALI) scale in the severity and prognosis of severe acute respiratory syndrome (S.ARS). Methods The clinical data of 38 SARS patients, including survivors (24 cases) and no survivors (14 cases) were collected and evaluated with APACHE Ⅲ and ALI scoring systems. The correlation of scores and prognosis was evaluated. Results The scores of APACHE Ⅲ in the non survivors were higher remarkably than those in the survivor group(P<0.001).The scores of APACHE Ⅲ had positive correlation with the overall fatality rate. When the scores of APACHE Ⅲ was higher than 60，the mortality increased obviously (χ²=3.886, P<0.05). Elderly patients with SARS who were over 60 years old had a high mortality(χ²=8.660, P<0.05).The scores of ALI in the non survivors had not statistical significance than those in the survivor group (P=0.127). Conclusions The score of APACHE Ⅲ in the SARS are correlated with the patient's condition and prognosis. Elderly patients with SARS have a high mortality.

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