| 许青,徐爱强,宋立志,张丽,肖作奎,王常银,李漫时,王爱莲,李震.山东省实施儿童风疹疫苗免疫后风疹发病年龄变化趋势的分析[J].中华流行病学杂志,2005,26(11):861-863 |
| 山东省实施儿童风疹疫苗免疫后风疹发病年龄变化趋势的分析 |
| Analysis on the changing of age patterns among rubella patients after rubella vaccine immunization for children in Shandong province, China |
| 收稿日期:2005-04-11 出版日期:2014-09-16 |
| DOI： |
| 中文关键词: 风疹疫苗免疫 年龄变化趋势 先天性风疹综合征 |
| 英文关键词: Rubella vaccine immunization Age distribution trend Congenital rubella syndrome |
| 基金项目:山东省医药卫生科研基金资助项目(1999CA1DDB1) |
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| 中文摘要: |
| 目的 分析山东省自1995年开始实施儿童风疹疫苗免疫后风疹发病年龄的变化趋势. 方法 对1999-2004年通过麻疹疫情专报系统得到的风疹疫情资料以及风疹疫苗接种情况进行分析. 结果 1999-2004年山东省风疹年平均报告发病率为0. 59/10万, 多为暴发(占总病例数的81. 17%);发病主要集中在7～15岁学龄儿童(77. 77%), 7岁以下发病较少(占7. 93%), 发病年龄中位数分别为10. 37岁、11. 66岁、11. 41岁、12. 81岁、14 28岁和13. 96岁, 发病高峰年龄逐年后移, 成人发病有所增加;学龄前儿童风疹疫苗基础免疫估算接种率约为60%, 学龄儿童约为20%. 结论 风疹发病年龄后移, 将威胁育龄期妇女, 增加发生先天性风疹综合征的危险性;应在继续做好儿童风疹免疫的同时, 积极开展育龄期妇女风疹抗体筛查及疫苗接种工作. |
| 英文摘要: |
| Objective To analyze the changing of age patterns among rubella patients after implementing rubella vaccine immunization to children in Shandong province since 1995. Methods Epidemiologic data on rubella through surveillance system for suspected measles from 1999 to 2004 and data on rubella vaccination were used and analyzed. Results The annual average incidence rate of rubella from 1999 to 2004 had been 0. 59 per 100 thousands population while 81. 17% of cases were concentrated during the outbreaks. 77. 77% of the cases were school children between 7-15 years old and 7. 93% of the cases were under 7 years old. The age-median of cases were 10. 37, 11. 66, 11. 41, 12. 81, 14. 28 and 13. 96 years old from 1999 to 2004, respectively. The estimated coverage of rubella vaccine for pre-school children was about 60 % but only 20 % were for school children. Conclusion The peak age of cases moved from youth towards adolescence which indicated that women with child-bearing age might have been under risk of developing the congenital rubella syndrome (CRS). It is necessary to carry out screening test of rubella antibody and vaccination to women with child-bearing age and the immunization strategy should be established to guide the control of rubella and CRS. |
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