| 江佳富,吴晓明,左曙青,王日明,陈立泉,王炳才,敦哲,张泮河,郭天宇,曹务春.褐家鼠种群特征与汉坦病毒感染的关联分析[J].中华流行病学杂志,2006,27(3):196-199 |
| 褐家鼠种群特征与汉坦病毒感染的关联分析 |
| Study on the association between hantavirus infection and Rattus norvegicus |
| 收稿日期:2005-07-28 出版日期:2014-09-12 |
| DOI： |
| 中文关键词: 汉坦病毒 褐家鼠 危险因素 |
| 英文关键词: Hantavirus Rattus norvegicus Risk factors |
| 基金项目:国家自然科学基金资助重大项目(30590374);北京市自然科学基金重点资助项目(7021004,06G0668) |
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| 中文摘要: |
| 目的 了解汉坦病毒(HV)优势宿主褐家鼠感染HV的相关危险因素。 方法 采集北京不同地区、生境捕获的褐家鼠, 用统一的调查表记录宿主动物及环境特征, 采用针对HVM基因片段的巢式RT-PCR法检测其带病毒情况, 运用SPSS软件多因素非条件logistic回归分析。结果 在所调查的10种相关因素中, 6种与褐家鼠HV感染相关。多因素非条件logistic回归分析结果显示: 成年鼠、处于繁殖期、体表皮肤有伤痕是褐家鼠HV感染的危险因素。雄性睾丸位于阴囊内与雄性HV感染有非常高的危险度(OR=30.92)。发情期雄性个体的体表疤痕率高于非发情期个体(P=0.049),两者的交互作用与HV感染相关有统计学意义(P<0.001)。结论 从现场多途径观察研究证实: HV在褐家鼠中存在平行传播, 雄性的侵犯行为促进HV的传播。 |
| 英文摘要: |
| Objective To further understand the association of hantavirus (HV) harbored and
transmitted in wild brown rats. Methods Rattus norvegicus ( n=570) were trapped in 10 sites in Beijing.
RT2PCR was used to test rodent lung samples for hantavirus infection. Unconditional multivariate logistic
regression analysis was performed,with PCR positive as the dependent variable and the characteristics of
Rattus norvegicus population as independent variables. Results The overall HV prevalence in Rattus
norvegicus was 9.1%(52/570). Significant association between HV infection in Rattus norvegicus and
some biological characteristics of host population was observed. Adult Rattus norvegicus had a higher HV
prevalence than juveniles. Males in the reproduction periods and rats with wounds were more likely to be
infected with HV than others. Conclusion It was further confirmed that there existed parallel transmission
of HV in Rattus norvegicus hosts. Aggression might be the primary mode of HV transmission among male
Rattus norvegicus. |
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