文章摘要
刘小宁,高海青,李保应,张志勉,高西美,米丰花,刘远萍,王敏,伊永亮.545名健康中老年人大动脉脉搏波速度的测定[J].中华流行病学杂志,2006,27(4):356-358
545名健康中老年人大动脉脉搏波速度的测定
Determination of the aortic pnlse wave velocity in 545 healthy subjects
收稿日期:2005-09-01  出版日期:2014-10-17
DOI:
中文关键词: 动脉硬化  脉搏波速度  动脉僵硬度
英文关键词: Arteriosclerosis  Pulse wave velocity  Stiffness
基金项目:
作者单位E-mail
刘小宁 中国医学科学院阜外心血管病医院  
高海青 山东大学齐鲁医院老年病科 gaohaiqing52@yahoo.com.cn 
李保应 山东大学齐鲁医院老年病科  
张志勉 山东大学齐鲁医院查体中心  
高西美 山东大学齐鲁医院查体中心  
米丰花 山东大学齐鲁医院查体中心  
刘远萍 山东大学齐鲁医院老年病科  
王敏 山东大学齐鲁医院老年病科  
伊永亮 山东大学齐鲁医院老年病科  
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中文摘要:
      目的了解健康中老年人各年龄段大动脉脉搏波速度(PWV)值与性别的关系以及随年龄变化的趋势。方法按照正常人标准筛选出正常健康人545名(男395名,女150名),年龄31- 85岁,平均年龄(63.93±10.99)岁,采用脉搏波速度测定仪Complior测定颈-股动脉脉搏波速度。结果健康人群大动脉PWV平均值为(11.62±2.97)m/s。40岁以上中老年男女PWV值差异无统计学意义,30-39岁组女性PWV低于男性,无论男女PWV均与年龄正相关。根据PWV与年龄的回归方程,已获得不同年龄段PWV的正常参照值。结论健康中老年人群大动脉PWV受年龄影响较大,与性别关系不大,应按照不同年龄段建立其正常参照值。年龄与PWV的正相关,随着年龄增加,主动脉僵硬度增加,弹性下降,PWV加速。
英文摘要:
      Objective To understand the aortic pulse wave velocity(PWV) in mid-aged and elderly populations and to study the correlation between gender and PWV and the tendency of PWV on different age groups. Methods According to the clinical trial guideline,we selected 545 healthy subjects (age,31-85 years,395 men and 150 women), and measured carotid-femoral PWV, using Complior. Results The average value of PWV in Chinese healthy subjects was 11.62±2.97 m/s. There was no significant difference in the PWV values between males and females who were older than 40 years,but the values of PWV were lower in females than in males in the 30-39 year-old group. PWV was positively correlated with age. In the present study,the reference values of PWV were established in the different age groups,based on the regression equations between PWV and age. Conclusion Aortic pulse wave velocity seemed to be influenced by age but hardly influenced by gender in healthy subjects,so that the reference value of PWV should be established according to the different age groups. When aorta got stiffer,the value PWV got larger accordingly when age was increasing.
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