| 张之伦,朱向军,丁亚兴,解晓华,高志刚,李永成,张颖,夏卫东,刘勇.天津市甲型肝炎免疫预防控制措施效果评价[J].中华流行病学杂志,2007,28(10):1000-1003 |
| 天津市甲型肝炎免疫预防控制措施效果评价 |
| Evaluation an the role of hepatitis A vaccine in the prevention and control of hepatitis A in Tianjin city |
| 收稿日期:2007-05-24 出版日期:2014-09-12 |
| DOI： |
| 中文关键词: 甲型肝炎疫苗 免疫预防 效果评价 |
| 英文关键词: Hepatitis A vaccine Immune prevention Evaluation of effectiveness |
| 基金项目: |
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| 中文摘要: |
| 目的 评价天津啊实施甲型肝炎(甲肝)免疫策略后控制甲肝的效果。方法 分析天津1990—2006年甲肝疫情资料，评价疫情报告系统，估算甲肝疫苗目标人群接种率，对比1999年和2005年15岁以下健康人群甲肝抗体水平。结果 天津市甲肝发病率从1990年的25.26/10万降到2006年的0.82/10万，甲肝在病毒性肝炎中的比例从1990年的30.43%降到2006年的1.05%；估算全市目标人群甲肝疫苗接种率平均为72.7%；2005年15岁以下人群甲月r抗体阳性串达到61.84%，明显高于1999年的29.90%。结论 天津市5年甲肝疫苗免疫策略的实践成功控制了甲肝流行。 |
| 英文摘要: |
| Objective To evaluate the effects of prevention and control strategies on hepatitis A.Methods Surveillance data on hepatitis A from 1990 to 2006 in Tianjin was analyzed,and the coverage rate of hepatitis A vaccine among targeted population was estimated,to campare the anti-HAV IgG level of children younger than 15 years old in 1999 and in 2005.Results showed that a) the morbidity of hepatitis A decreased from 25.26/105 in 1990 to 0.82/105 in 2006;b) the ratio of hepatitis A in viral hepatitis decreased from 30.43'16 in 1991 to 1.05% in 2006;c) the estimated coverage rate was 72.7%;d) the positive rate of anti-HAV among children younger than 15 years old in 2005 was distinctly higher than that in 1999.Conclusion Positive results showed that it was successful to use hepatitis A vaccine as the strategy to prevent and control hepatitis A in the past five years in Tianjin. |
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