文章摘要
唐浏英,许文波.腺病毒分子流行病学研究[J].中华流行病学杂志,2008,29(8):836-838
腺病毒分子流行病学研究
Molecular epidemiological research on human Adenovirus
投稿时间:2008-01-06  
DOI:
中文关键词: 腺病毒;分子流行病学
英文关键词: Adenovirus;Molecular;epidemiology
基金项目:国家“九五”科技攻关课题资助项目(96-906-02-05)
作者单位E-mail
唐浏英 中国疾病预防控制中心病毒病预防控制所,北京,100052 xudezh@fmmu.edu.cn 
许文波 中国疾病预防控制中心病毒病预防控制所,北京,100052  
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中文摘要:
      腺病毒引起的儿童肺炎在20世纪5060年代比较猖獗,发病率和病死率很高,中国报道的病死率达16.6%~33.3%。80年代后发病率和病死率有所降低,但近几年腺病毒感染人数又有所回升,甚至出现了腺病毒新的变异株。据报道,2006年5月美国纽约市1名出生12d的女婴死于腺病毒14型引起的上呼吸道感染;2007年3—6月在俄勒冈、华盛顿和德克萨斯州有140例患者感染腺病毒14型,
英文摘要:
      objective To investigate the risk factors in postoperative cognitive dysfunction(POCD) induced by patient self-controlled intravenous analgesia (PCIA).Methods A case-control sfudy included 103 patients with POCD(P group),assessed by Mini-Mental-State test and 103 cognitive normal controls (NP group).The cases and controls were matched for age, gender, history of operation and PCIA volume dose.The relationship between POCD and various factors was analyzed by univariate and multivariate analysis.Spss 11.5 of statistical software was used for data analysis.Results Data from univariate analysis showed that the history of cerebral trauma, education level and VAS score had significant differences between P group and NP group.Multivariate analysis conformed that the history of cerebral trauma, VAS score and education level were significantly related to POCD induced by PCIA and their ORs(95% Cl) were 4.261(1.344- 13.508),2.364(1.209- 4.624),0.312(0.170-0.573)respectively.Conclusion Patient's history of cerebral trauma and low VAS score were independent risk factors of POCD induced by PCIA and high education level seemed to be a protective factor.
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