| 刘涛,陈维清,何艳辉,丁鹏,凌文华.孕妇被动吸烟与小于胎龄儿关系的Meta分析[J].中华流行病学杂志,2009,30(1):68-72 |
| 孕妇被动吸烟与小于胎龄儿关系的Meta分析 |
| A Meta-analysis on the association between maternal passive smoking during pregnancy and small-for-gestational-age infants |
| 收稿日期:2008-09-25 出版日期:2014-09-11 |
| DOI： |
| 中文关键词: 被动吸烟 小于胎龄儿 Meta分析 |
| 英文关键词: Passive smoking Small-for-gestational-age infants Meta-analysis |
| 基金项目:国家自然科学基金资助项目(30872164);中华医学基金会(CMB)资助项目(00-729) |
| 作者 | 单位 | E-mail | | 刘涛 | 510080 广州, 中山大学公共卫生学院医学统计与流行病学系, 公共卫生学院 | | | 陈维清 | 510080 广州, 中山大学公共卫生学院医学统计与流行病学系, 公共卫生学院 | chenwq@mail.sysu.edu.cn | | 何艳辉 | 510080 广州, 中山大学公共卫生学院医学统计与流行病学系, 公共卫生学院 | | | 丁鹏 | 510080 广州, 中山大学公共卫生学院医学统计与流行病学系, 公共卫生学院 | | | 凌文华 | 510080 广州, 中山大学公共卫生学院医学统计与流行病学系, 公共卫生学院 | |
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| 中文摘要: |
| 目的 探讨孕妇孕期被动吸烟与小于胎龄儿之间的关系,分析不同孕期和不同地点被动吸烟的效应.方法 利用Meta分析方法综合分析国内外8篇关于孕妇孕期被动吸烟与小于胎龄儿关系的回顾性研究文献.结果 孕妇孕期被动吸烟与小于胎龄儿之间的粗合并效应值OR=1.45(95%CI:1.05～2.01),调整合并效应值OR=1.76(95%CI:1.15～2.69);孕妇孕早期被动吸烟的合并效应值OR=1.85(95%CI:1.25～2.72),孕中晚期被动吸烟的合并效应值OR=2.12(95%CI:1.43～3.13);家庭和工作中被动吸烟与小于胎龄儿之间的关系均没有统计学意义.结论 孕妇孕期被动吸烟可增加发生小于胎龄儿的危险性.除了家庭和工作环境外,还应注意其他环境的被动吸烟. |
| 英文摘要: |
| Objective To study the association between maternal passive smoking during pregnancy and the small-for-gestational-age (SGA) infants and to analyze independent factors on duration,in different areas.Methods Totally,8 retrospective studies published in PubMed (no year limited),OVID-MEDLINE (no year limited),CNKI (from 1911 to 2008),VIP (from 1989 to 2008),and CBM (no year limited),on maternal passive smoking during pregnancy and SGA were analyzed synthetically by Meta-analysis.Results The unadjusted pooled OR value on the association between maternal passive smoking during pregnancy and SGA was 1.45 (95%CI: 1.05-2.01).Data showed that the adjusted pooled OR value was 1.76 (95%Ch 1.15-2.69).Maternal passive smoking in early pregnancy was a risk factor for SGA(OR=1.85,95%Ch 1.25-2.72),and so was the exposure in mid or late pregnancy (OR=2.12,95%Ch 1.43-3.13).No statistically significant relationship between SGA and passive smoking at home or at workplace was found.Conclusion Avoiding passive smoking in pregnancy for mothers could reduce the possibility of delivering SGA infants.Other than at home or at workplace,problem of passive smoking in other places should also be brought up. |
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