文章摘要
杨智聪,毛新武,李铁钢,李海麟,刘于飞,吴新伟,袁俊,谢朝军,李魁彪,蒋丽云,陈艺韵,湛柳华,肖晓玲,刘建平,沈纪川,蔡文峰,王鸣.国内首起本地感染甲型H1N1流感疫情的流行病学分析[J].中华流行病学杂志,2009,30(7):684-686
国内首起本地感染甲型H1N1流感疫情的流行病学分析
Epidemiological charaeteristic of first case of Iocally identmed A/HlNl secondary casea caused by imported source of tnfection in China
收稿日期:2009-06-02  出版日期:2014-10-16
DOI:10.3760/cma.j.issn.0254-6450.2009.07.009
中文关键词: 甲型HINl流感  本地感染  流行病学特征
英文关键词: HlNl  Autochthonous infection  Epidemiologic feature
基金项目:
作者单位E-mail
杨智聪 510080,广州市疾病预防控制中心  
毛新武 510080,广州市疾病预防控制中心  
李铁钢 510080,广州市疾病预防控制中心  
李海麟 510080,广州市疾病预防控制中心  
刘于飞 510080,广州市疾病预防控制中心 yjk@gzedc.org.cn 
吴新伟 510080,广州市疾病预防控制中心  
袁俊 510080,广州市疾病预防控制中心  
谢朝军 510080,广州市疾病预防控制中心  
李魁彪 510080,广州市疾病预防控制中心  
蒋丽云 510080,广州市疾病预防控制中心  
陈艺韵 510080,广州市疾病预防控制中心  
湛柳华 广州中越秀区疾病预防控制中心  
肖晓玲 广州中越秀区疾病预防控制中心  
刘建平 510080,广州市疾病预防控制中心  
沈纪川 510080,广州市疾病预防控制中心  
蔡文峰 510080,广州市疾病预防控制中心  
王鸣 510080,广州市疾病预防控制中心  
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中文摘要:
      目的 分析周内首起甲型HINl流感输入性传染源引发本地二代病例疫情, 探讨发病规律和流行特征。方法 设计统一调查表, 采用面对面病例个案调查和现场调查, 以指示病例为起点进行追踪, 描述传播过程及各因素与发病之间的关系, 分析疫情的流行病学特征。结果 发现指示病例后, 密切接触者中有2人出现发热和上呼吸道症状且咽拭子甲型HINI流感病毒核酸检测阳性, 被确诊为国内茸起本地感染甲趔H1Nl流感病例。2名密切接触者未采取任何防护措施与指爪病例多次近距离接触, 且现场通风不良;发病潜伏期37~57 h, 临床表现均较指示病例轻。经采取严格防疫措施, 未见新发病例。结论 此次事件为由输入性传染源引起的本地感染疫情, 无防护近距离空气及飞沫传播为主要传播方式, 空气流通不良的密闭李间是高危场所。
英文摘要:
      Objective To study the first locally identifed A/HlNl secondary cases outbreak in China.Methods Interview and field investigation were integrated to describe the whole process of transmission on each case and to illustrate the relationships between the onset of the disease and the retated factors.Results Two contact persons appearanced fever and whose throat swabs were tested positive to HlN1 viral nucleic acid.The two had ahistory of contact in a short distanee with the initial imported case without any protective measure in the poor air ventilation.The patients clinical situation was slight.The incubation was between 37 hours and 57 hours.N0 other newcase was found after intervention as isolation and antisepsis were taken.Conclusion This event was proved to be an outbreak of local H1Nl secondary cases caused by the imported case.The main mode of transmission was personal contact in a short distance without protection, through air and droplet.The lOCUS with poor air ventilation was high risk place.Contact persons should be observed seven days and tested continuously.1nfectivity and pathogenicity of the A/HlN1 virus were limited and appeared weakened by ations.Patient’s condition was related with persistence and frequency of contact with the infection sources.Enhancing management of contact persons, health education。early diagnose, early treatment and early insulation were effective measures of controling and prenventing the spread A/H1N1.
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