文章摘要
陈晓,曾志磊,谢鹏.西尼罗病毒感染的抗体检测方法研究进展[J].中华流行病学杂志,2009,30(9):969-972
西尼罗病毒感染的抗体检测方法研究进展
A review on assays for detecting anfibodies of West Nile virus infection
投稿时间:2008-12-18  修订日期:2007-09-17
DOI:
中文关键词: 西尼罗病毒;抗体;检测
英文关键词: West Nile virus;Antibody;Detection
基金项目:国家“十一五”高科技发展计划(2006AA022196)
作者单位E-mail
陈晓 重庆医科大学附属第一医院神经内科 400016  
曾志磊 重庆医科大学附属第一医院神经内科 400016  
谢鹏 重庆医科大学附属第一医院神经内科 400016 peng.xie58@gmail.com 
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中文摘要:
      西尼罗病毒(West Nile virus,WNV)是一种单股正链RNA病毒,属黄病毒科(Family Flaviviridae)、黄病毒属(Genus Flavivirus),与日本乙型脑炎病毒(Japanese encephalitis virus,厄V)、墨累谷脑炎病毒(Murray Valley encephalitis virus,MVEV)、圣路易斯脑炎病毒(St.Louis encephalitis virus,SLEV)、昆津病毒(Kunjin virus,KV)同属JEV血清群。病毒核酸编码3种结构蛋白和7种非结构蛋白。3种结构蛋白分别是病毒壳蛋白(c)、包膜蛋白(E)和前膜蛋白(prM)。
英文摘要:
      Objective To investigate whether green tea consumption can reduce the risk of adult leukemia. Methods A hospital-based matched case-control study was conducted in 2005一2006. We recruited 107 confirmed leukemia cases and 110 inpatient controls with orthopedic disease without leukemia or other malignancy matched on gender, age and hospitals that patients stayed. Related information were gathered on quantity, duration and frequency of tea consumption, demographic characteristics, exposure to radiation and occupational hazards, medications, using a validated questionnaire by face-to-face interview. Univariate and multivariate unconditional logistic regression analysis were used to estimate odds ratios (ORs) and associated 95% confidence intervals(Cls) with SPSS 11.5 software. Results Compared with non-tea-drinkers, the OR of those who consumed green tea was 0. 58 ( 95 % CI:0.34-1.00,P< 0.05) under univariate statistical analysis. The OR was 0. 52 ( 95 96 CI:0.28-0.98, P=0.04),using logistic regression to count for age, gender, residential area, smoking, level of education, exposure to radiation, benzene and organo-phosphorus. Compared with non-drinkers, the risk of adult leukemia declined with increasing quantity,duration,and frequency of green tea consumption. Tests for trend on dose-response was statistically significant (P<0.01)Conclusion A higher consumption of green tea seemed to be associated with a declined risk of adult leukemia. Tea consumption might be of help to human health planning projects.
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