文章摘要
曹晓斌,殷文渊,庞琳,张从斌,徐金水,肖永康,王常合,罗巍,张波,张瑞敏,李志军,柔克明,吴尊友.中国九城市1301名社区美沙酮维持治疗门诊患者偷吸海洛因及影响因素分析[J].中华流行病学杂志,2010,31(3):269-272
中国九城市1301名社区美沙酮维持治疗门诊患者偷吸海洛因及影响因素分析
Risk factors which were associated with heroin use during the methadone maintenancetreatment among 1301 patients in 9 cities of China
收稿日期:2009-09-15  出版日期:2014-09-12
DOI:
中文关键词: 美沙酮维持治疗  海洛因  影响因素
英文关键词: Methadone maintenance treatment  Heroin use  Risk factors
基金项目:中央补助地方公共卫生专项经费艾滋病防治项目;美国疾病预防控制中心伞球艾滋病项目(USCDCGAP6.3.1 C)
作者单位E-mail
曹晓斌 北京, 中国疾病预防控制中心性病艾滋病预防控制中心, 100050  
殷文渊 北京, 中国疾病预防控制中心性病艾滋病预防控制中心, 100050  
庞琳 北京, 中国疾病预防控制中心性病艾滋病预防控制中心, 100050  
张从斌 云南省药物依赖防治研究所社会服务部  
徐金水 江苏省疾病预防控制中心性病艾滋病防治科  
肖永康 安徽省疾病预防控制中心艾滋病防治科  
王常合 北京, 中国疾病预防控制中心性病艾滋病预防控制中心, 100050  
罗巍 北京, 中国疾病预防控制中心性病艾滋病预防控制中心, 100050  
张波 云南省药物依赖防治研究所社会服务部  
张瑞敏 云南省药物依赖防治研究所社会服务部  
李志军 美国疾病预防控制中心全球艾滋病项目  
柔克明 北京, 中国疾病预防控制中心性病艾滋病预防控制中心, 100050  
吴尊友 北京, 中国疾病预防控制中心性病艾滋病预防控制中心, 100050 wuzy@263.net 
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中文摘要:
      目的 了解社区美沙酮维持治疗患者治疗期间偷吸海洛因的情况及其影响因素.方法 在江苏、安徽、云南3省9个城市社区美沙酮维持治疗门诊中抽取1301名符合条件的患者进行问卷调查与随机尿吗啡定性检测.收集一般人口学、艾滋病/毒品滥用相关高危行为、参加美沙酮维持治疗情况、抑郁与焦虑及偷吸海洛因等信息.结果 1301名调查对象中男性居多(76.2%),年龄(34.6±6.5)岁,受教育程度以初中及以下为主(71.7%).平均维持治疗剂量(48.1±29.4)mg/d,目前治疗剂量自我满意度平均得分为8.6,尿吗啡检测阳性率为27.7%.有抑郁和焦虑症状者比例分别为38.3%和18.4%,抑郁合并焦虑症状的比例为14.2%.婚姻状况、治疗时间的长短、目前治疗剂量自我满意度及是否曾退出治疗对偷吸海洛因影响的差异有统计学意义,而性别、教育程度及治疗剂量对偷吸海洛因的影响差异无统计学意义.不同省份间影响偷吸海洛因的因素有所不同,但对当前剂量自我满意度是共同的影响因素.结论 提高门诊服务质量及服药依从性、延长参加治疗的时间、提高患者对治疗剂量的满意度及避免脱失对减少治疗期间偷吸海洛因有重要意义.
英文摘要:
      Objective To determine the proportion of heroin use among patients who were involved in community-based methadone maintenance treatment (MMT) program and to identify the risk factors associated with heroin use. Methods This study was conducted in 9 MMT clinics within 3 provinces. Thirteen hundred and one patients who met the study criteria were selected from each of the five groups with different dosages of methadone users. An administrative questionnaire was applied to explore the demographics,drug abuse-related behaviors and MMT services received by the clients,etc. The prevalence of depression and anxiety among the clients were also collected by SAS and SDS. Urine samples were collected as a biological marker to indicate if heroin had been used. /b>Results Of the 1301 patients,76.2% were males. The mean age was (34.6±6.5) years while 71.7% had an education level of primary school or below. The average daily dosage of methadone was (48.1±29.4) mg and self-satisfied evaluation score on treatment was 8.6. On average,27.7% urine samples showed positive opiate evidence. Marital status,employment status,treatment retention,self-satisfied evaluation score on dosage and dropout history were found to be significantly associatedwith heroin use,while gender,education level and dosage had no significant association with heroin use. It seemed that risk factors that associated with heroin use were different from areas to areas. Conclusion High quality MMT clinic services,high self-satisfied score,longer treatment retention and low dropout rate seemed to have the effects of reducing the risk of ongoing heroin abuse under the methadone maintenance treatment program.
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