| 黄芳,郭婧,崔淑娟,吕燕宁,高志勇,李伟红,严寒秋,曲梅,石伟先,卢桂兰,张新,张代涛,田丽丽,钱海坤,杨鹏,庞星火,王全意.北京市甲型H1N1流感病毒病原学监测分析[J].中华流行病学杂志,2010,31(5):494-496 |
| 北京市甲型H1N1流感病毒病原学监测分析 |
| Etiological characteristics of influenza A (H1N1) 2009 virus in Beijing |
| 收稿日期:2010-01-12 出版日期:2014-09-18 |
| DOI：10.3760/cma.j.issn.0254-6450.2010.05.004 |
| 中文关键词: 甲型H1N1流感病毒 荧光定量PCR 病原学 |
| 英文关键词: Influenza A (H1N1) 2009 Real-time PCR Etiology |
| 基金项目:欧盟第6框架基金(015396)；上海市气象局科技开发项目(YJ201101)；公益性行业科研专项(GYHY201206027) |
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| 中文摘要: |
| 目的 分析北京市2009年5一12月甲型HINl流感病毒检测结果，探讨流感大流行时期甲型H1N1流感病原流行病学特征。方法 2009年5月1日至2009年12月27日，共采集101852份咽拭子样本，北京市传染病网络实验室利用荧光定量PCR方法检测，并做统计分析。结果 101852份检测样本中，甲型H1N1流感病毒核酸阳性9843份，总阳性率为9.66%，其中5—6月阳性率为2.85%，7—8月阳性率为3.32%，9—10月阳性率为8.35%。11月阳性率为29.67%，12月阳性率为24.33%。可疑病例排查阳性率为8.40%，病例密切接触者阳性率为4.75%，门诊流感样病例(ILI)阳性率为11.46%，聚集性发热病例及其他病例阳性率为7.33%。年龄分布以5～14岁和15～24岁年龄段为主，男女性别构成比为1.5：1。结论 北京市2009年5—11月甲型H1N1流感病毒感染呈持续上升，12月呈下降趋势，具有一定的流行病学特征。 |
| 英文摘要: |
| Objective To analyze the results of detection on influenza A (H1N1)2009 virus in Beijing from May 2009 to December 2009 and to understand the epidemiologic characteristics during the pandemic period.Methods The study was conducted from the May 1 to December 27,2009.A total of 101 852 throat swab samples were detected with the real-time RT PCR assay by the Beijing Network Laboratory.Data was statistically analyzed.Results 9843 samples showed influenza A (H1Ni)2009 positive,with an overall positive rate as 9.66%.In terms of the positive rates,they were 2.85% from May to June,3.32% from July to August and 8.35% from September to October.The peak month fell in November (29.67%)and December (24.33%).The positive rates among the following subpopulations were:8.40% among the suspected cases,4.75% among close contact cases,11.46% among the influenza-like illness cases and 7.33% among the cluster cases with fever.Positive cases mainly fell in age groups 5-14 and 15-24.The ratio of male to female was 1.5:1.Conclusion During the pandemic period of influenza A (H1N1)2009,positive cases gradually increased during May to November but slowly decreasing in December. |
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