| 徐丽丽,袁秀琴,朱军,李小洪,王艳萍,周光萱,缪蕾,杨义.中国部分地区1996--2007年腹裂畸形患病率变化趋势研究[J].中华流行病学杂志,2011,32(3):268-270 |
| 中国部分地区1996--2007年腹裂畸形患病率变化趋势研究 |
| Incidence and its trends on gastroschisis in some parts of China,1996—2007 |
| 收稿日期:2010-10-25 出版日期:2014-09-11 |
| DOI： |
| 中文关键词: 腹裂 患病率 |
| 英文关键词: troschisis Incidence |
| 基金项目:“十一五”园家科技支撑计划(2006BAl05A01) |
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| 中文摘要: |
| 目的 了解中国围产儿腹裂畸形的发生情况,并分析其相关因素.方法 以医院为基础的出生缺陷监测方法收集资料,利用趋势x2检验对1996-2007年中国围产儿腹裂畸形患病率变化趋势进行研究、泊松回归模型对几个主要影响腹裂围产儿分布的因素进行危险度分析.结果 共监测新生儿6 308 594例,其中腹裂畸形1601例,总患病率为2.54/万,12年内没有显著增长趋势.城乡、男女及孕产妇不同年龄组之间患病率的差异均有统计学意义,城市患病率(1.91/万)低于农村(3.87/万),男性患病率(2.20/万)低于女性(2.62/万),孕产妇年龄＜20岁组患病率(10.38/万)高于其他各年龄组患病率.城市腹裂畸形患病率低于农村(RR=0.58);男性腹裂畸形患病率低于女性(RR=0.76);孕产妇年龄＜20岁组围产儿腹裂患病率是30～34岁组的11.43倍(RR=11.432).结论 1996-2007年中国围产儿腹裂患病率没有显著增长,但在性别、城乡及产妇年龄之间存在差异.年龄＜20岁的产妇生育腹裂胎儿的危险性最大. |
| 英文摘要: |
| Objective To investigate the incidence and its secular trends of gastroschisis in Chinese perinatal infants.Methods Data on perinatal infants was collected at hospitals under surveillance program in Chinese Birth Defects Monitoring Network from 1996 to 2007.Data on incidence,trend and related factors of gastroschisis in perinatal infants were carried out.Both x2 test and Poisson regression model were used to test the differences between residential areas,sex and maternal age.Both x2 trends test and Poisson regression model were applied to analyze the trends.Results A total of 6 308 594 perinatal infants were monitored during 1996-2007,including 1601 infants with gastroschisis to show the incidence as 2.54 per 10 000 births.The overall prevalence of gastroschisis in China did not change remarkably during the period of our research.The incidence rates of gastroschisis were significantly different between urban and rural areas,between different sex and different maternal age groups.The incidence of gastroschisis was lower in urban area than in rural area (RR=0.58) and lower in female fetuses than in male fetuses (RR=0.76),highest in the group younger than 20 years of age,which was 11.43 times than incidence of the 30-34 age group (RR=11.432).Conclusion The overall prevalence of gastroschisis in China did not show remarkable change during 1996-2007 but the incidence of gastroschisis a bit increased in the area of study and significant differences were seen in different sex,regions and maternal age groups.Mothers aged younger than 20 years old appeared to be a significant risk factor for the occurrence of gastroschisis. |
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