不同肥胖测量指标对北京市社区人群动脉僵硬度的评价

郑瑾; 叶平; 肖文凯; 骆雷鸣; 吴红梅

文章摘要

郑瑾,叶平,肖文凯,骆雷鸣,吴红梅.不同肥胖测量指标对北京市社区人群动脉僵硬度的评价[J].中华流行病学杂志,2011,32(5):465-468

不同肥胖测量指标对北京市社区人群动脉僵硬度的评价

Correlations between different obese indexes and arterial stiffness among populations at the community level

收稿日期:2010-11-26 出版日期:2014-09-10

DOI：

中文关键词: 肥胖动脉僵硬度社区人群

英文关键词: Obesity Arterial stiffness Community population

基金项目:

作者	单位	E-mail
郑瑾	解放军总医院南楼临床部心血管二科, 北京 100853
叶平	解放军总医院南楼临床部心血管二科, 北京 100853	yeping@sina.com
肖文凯	解放军总医院南楼临床部心血管二科, 北京 100853
骆雷鸣	解放军总医院南楼临床部心血管二科, 北京 100853
吴红梅	解放军总医院南楼临床部心血管二科, 北京 100853

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中文摘要:

目的探讨社区人群肥胖及其不同测量指标与动脉僵硬度的相关性.方法北京市4个社区参加体检的2664名经知情同意的研究对象(男性1379名,女性1285名),平均年龄(53.19±15.73)岁,测量身高、体重、腰围(WC)、臀围,并计算其体重指数(BMI)、腰围臀围比(WHR),应用自动PWV分析仪测定颈-股动脉脉搏波传导速度(cfPWV),分析不同肥胖指标(BMI、WC、WHR)与cfPWV的关系.结果 2664名受试者中,BMI(r=0.0829,P＜0.01)、WC(r=0.2659,P＜0.01)、WHR(r=0.2749,P＜0.01)与cfPWV均呈正相关.单因素分析结果显示:将研究对象分为A组(cfPWV≤12 m/s)、B组(cfPWN＞12 m/s),与A组相比,B组的WC、WHR高于A组,差异有统计学意义(P＜0.05).BMI在A组与B组之间差异无统计学意义(P≥0.05).逐步回归分析显示:WC是cfPWV的危险因素,独立于性别、年龄、收缩压、高密度脂蛋白胆固醇、餐后2h血糖因素存在.结论该社区人群中肥胖是动脉僵硬度的独立危险因素,其中不同的肥胖测量指标与动脉僵硬度的相关性不同.

英文摘要:

Objective The aim of this study was to investigate the relationship between obesity [measured by body mass index(BMI), waist circumference(WC), waist-to-hip ratio(WHR)]and arterial stiffness on community populations in Beijing area. Methods In a cross-sectional study of 2664 subjects(1379 men and 1285 women)aged(53.19 ± 15.73 years, mean±standard deviation), BMI, WC, WHR and other cardiovascular risk factors, were measured and carotidfemoral pulse wave velocity(cfPWV)was measured to assess the arterial stiffness. All the data were analyzed with linear correlation analysis, univariate analysis and stepwise regression method to explore the relationship between obese indexes and arterial stiffness. Results We noticed that a showed the existence of positive correlations between BMI(r=0.0829,P＜0.01)and cfPWV, WC(r=0.2659, P＜0.01)and cfPWV, WHR(r=0.2749, P＜0.01)and cfPWV, in univariate analysis,cfPWV was associated with WC≥85 cm(male)or ≥80 cm(famale)(P＜0.01), WHR≥0.90(male)or≥ 0.85(famale)(P＜ 0.01). Stepwise regression analysis revealed that WC was an independent risk factor of cfPWV, other than age, gender, systolic blood pressure, HDL-C, OGTT2h etc. Conclusion Our findings indicated that obesity was an independent risk factor of cfPWV, which was an early marker of cardiovascular and renal diseases, among community population in Beijing area. There were different relationships between obesity measurement parameters(BMI, WC, WHR)and cfPWV.

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