| 段松,韩晶,杨跃诚,项丽芬,叶润华,龚渝蓉,杨世江,杨忠桔,韩文香,杨建华,曹东冬,李维美,李洋,唐仁海,吴尊友,何纳.1989-2010年云南省德宏州艾滋病病毒感染者死因分析[J].中华流行病学杂志,2011,32(9):896-901 |
| 1989-2010年云南省德宏州艾滋病病毒感染者死因分析 |
| Causes of death among HIV-infected patients in Dehong prefecture, Yunnan province:1989-2010 |
| 收稿日期:2011-04-01 出版日期:2014-09-11 |
| DOI： |
| 中文关键词: 艾滋病 病死率 死因 |
| 英文关键词: Acquared immune deficiency sundrom Case fatality Causes of death |
| 基金项目:国家“十一五”科技重大专项（2008ZX10001-016，2008ZX 10001 -003） |
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| 中文摘要: |
| 目的 了解1989- 2010年云南省德宏州艾滋病病毒感染者/艾滋病患者(HIV/AIDS)20年病死率及死因变化。方法在“艾滋病综合防治数据信息管理系统”中，下载1989-2010年的历史卡片，对相关数据进行调查核实和统计分析。结果1989-2010年共报告现住址及户籍地为德宏州的HIV/AIDS 13493例，其中HIV8569例，死亡2036例；AIDS 4924例，死亡2251例。少数病例已存活达15～20年。2004年以前报告的发病病例中，死亡病例数高于存活病例数，而此后历年报告的发病病例中，存活病例数则高于死亡病例数。HIV/AIDS当年发病当年死亡的病例数占当年发病总病例数的比例在1989-2010年的20年间则表现出由低到高再到低的变化趋势，其中2001-2003年该比例均高于10.0％,2003年达到最高的18.9％，此后逐年稳步下降，2010年该比例为5.8％；而年初存活当年死亡的比例则自2007年起逐年下降。HIV/AIDS死亡病例中，因艾滋病而死亡的比例逐年上升而因吸毒过量而死亡的比例下降，其中，曾接受过CD4+T淋巴细胞计数检测和抗病毒治疗的比例也逐年上升，至2010年时分别达到89.9％和25.5％。结论德宏州HIV/AIDS病死率近年来呈下降趋势，扩大CD4+T淋巴细胞计数检测和抗病毒治疗、降低病死率仍是今后一个时期艾滋病防治工作重点。农村地区应加强AIDS死因监测。 |
| 英文摘要: |
| Objectives To analyze the fatality and causes of death related to comprehensive prevention and care programs among HIV-infected patients in Dehong prefecture of Yunnan province,from 1989 to 2010.Methods Data on HIV/AIDS death cases in Dehong prefecture were extracted from the "Chinese National Comprehensive HIV/AIDS Prevention and Care Information System" and were analyzed.Results From 1989 to the end of 2010,a total of 13 493 HIV/AIDS cases registered as local residents or currently living m Dehong, had been reported. Among them, 8569 were reported as HIV cases with 2036 deaths and the other 4924 were reported as AIDS cases with 2251 deaths. A few of the cases had survived for 15-20 years. By the end of 2010, the number of deaths was higher than the number of survivors among HIV/AIDS cases reported before 2004, whereas the number of survivors was higher than the number of deaths among HIV/AIDS cases reported in 2004 and there after. During the twenty years' period,the proportion of reported HIV/AIDS cases died in the same year showed a secular trend of being low-highest-low, rising up to ＞ 10.0％ in 200 1, peaking at 18.9％in 2003 and then continuously going down to 5.8％ in 2010. The proportion of HIV/AIDS cases who survived at the beginning but died later in the year was going down since 2007. The proportion of HIV/ AIDS deaths died directly from AIDS was increasing whereas the proportion of HIV/AIDS deaths dying directly from overuse of drugs was decreasing in the recent years. Among HIV/AIDS deaths, the proportion of ever received CD4+ T-cell testing and the proportion of ever having received antiretroviral treatment were also increasing in the past years, reaching to 89.9％ and 25.5％ in 2010,respectively.Conclusion The case fatality of HIV/AIDS was decreasing in the past years in Dehong prefecture. More efforts were needed to scale up the CD4+ T-cell count testing and antiretroviral treatment in order to further reduce both morbidity and mortality among HIV/AIDS patients in Dehong prefecture. It is critical to improve surveillance program on HIV/AIDS deaths in the rural. |
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