文章摘要
唐晓燕,康锴,李幸乐,陈豪敏,许汴利.河南省2006-2010年流行性乙型脑炎病例监测[J].中华流行病学杂志,2011,32(11):1128-1130
河南省2006-2010年流行性乙型脑炎病例监测
Surveillance on Japanese encephalitis in Henan province,2006-2010
收稿日期:2011-09-13  出版日期:2014-09-18
DOI:
中文关键词: 流行性乙型脑炎;流行病学
英文关键词: Japanese encephalitis;Epidemiology
基金项目:山东省医药卫生科技发展计划(2009一HE049)
作者单位E-mail
唐晓燕 河南省疾病预防控制中心传染病预防控制研究所, 郑州 450016 bianlixu@163.com 
康锴 河南省疾病预防控制中心传染病预防控制研究所, 郑州 450016  
李幸乐 河南省疾病预防控制中心传染病预防控制研究所, 郑州 450016  
陈豪敏 河南省疾病预防控制中心传染病预防控制研究所, 郑州 450016  
许汴利 河南省疾病预防控制中心传染病预防控制研究所, 郑州 450016  
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中文摘要:
      目的分析河南省流行性乙型脑炎(乙脑)流行特点及流行因素。方法 通过描述性流行病学方法分析2006-2010年河南省乙脑发病的流行病学特点及其影响因素,采用ELISA方法检测病例血液或脑脊液乙脑病毒IgM抗体。结果 2006-2010年共报告乙脑3099例,发病率波动在0.39/10万~ 1.08/10万,发病趋势呈波动性下降;信阳、南阳、洛阳3市为高发区,其发病数占总病例的60.12%;7-9月为流行高峰,占93.26%;全省发病以0~14岁为多(83.61%),洛阳市≥15岁年龄组发病升高明显(57.63%),与全省≥15岁年龄组发病构成比相比,经x2检验差异有统计学意义(x2=330.0341,P<0.05);全程接种乙脑疫苗的占4.95%,非全程接种的占15.28%,无疫苗接种和接种史不详的共占79.77%;实验室确诊病例占42.98%,临床诊断病例占45.95%,疑似病例占11.07%。结论河南省乙脑病例的分布呈现季节性、地域性和人群差异的特点。乙脑疫苗的基础免疫和加强免疫有待规范,病例实验室诊断率需要进一步提高。
英文摘要:
      Objective To analyze the epidemiological characteristics and risk factors of Japanese encephalitis (JE) in Henan province. Methods Epidemiological characteristics and related factors of JE cases in Henan province from 2006 to 2010 were analyzed with descriptive epidemiological method and JE IgM antibodies of the serum or cerebrospinal fluid of the cases were detected by ELISA. Results 3099 cases were reported in Henan province from 2006 to 2010.The incidence fluctuated from 0.39/100 000 to 1.08/100 000,and the incidence rate was decreasing.Patients were concentrated mainly in Xinyang,Nanyang and Luoyang cities,which accounted for 60.12% of the total.The peak season was in July-September, accounted for 93.26% of all the cases.Most cases were in 0-14 year old (83.61%) in the whole province.However,in Luoyang city,number of cases in the≥15 year old group,had an obvious increase (57.63%).Compared with the provincial data,significant difference was found between the two≥15 year old groups (x2=330.0341,P<0.05 statistically.20.23% of the JE cases were vaccinated but 75.54% of them did not complete the whole course.79.77% of the cases were not sure if they had received the vaccination. 42.98% of the JE cases were confirmed through laboratory tests but other 45.95% of them were clinically diagnosed, with the rest 11.07% were suspected cases.Conclusion The distribution of JE cases showed seasonal,regional characteristics and crowd differences in Henan province.Basic immunization and the program on strengthening immunization of JE should be further standardized.The laboratory diagnosis rate of JE cases should be further improved.
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