| 王涵,申丽洁,李伟,薛士鹏,王彦.云南省大理市洱海周边地区淡水螺广州管圆线虫感染调查[J].中华流行病学杂志,2011,32(11):1174-1174,1175 |
| 云南省大理市洱海周边地区淡水螺广州管圆线虫感染调查 |
| A survey of infection with Angiostrongylus cantonensis around Erhai Lake in Dali,Yunnan province |
| 收稿日期:2011-04-27 出版日期:2014-09-18 |
| DOI： |
| 中文关键词: 广州管圆线虫 感染源 洱海周边 |
| 英文关键词: giostrongylus cantonensis Infection sources Surrounding of Erh |
| 基金项目:国家自然科学基金(81072389)；江苏省高校自然科学研究重大项目(10KJA330034) |
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| 中文摘要: |
| 广州管圆线虫(Angiostrongylus cantonensis)是动物寄生虫，终宿主为哺乳动物，主要是鼠类，中间宿主是陆生螺类或淡水螺类，如福寿螺、玛瑙螺等 |
| 英文摘要: |
| Genome-wide association study is an important approach to identify common genetic variants that predispose to human disease.Because of the high cost of genotyping on hundreds of thousands of markers on thousands of subjects，a more cost-effective two-stage case-control design is applied by most genome-wide association studies.To describe the design and statistical methods of the two-stage case-control study，this paper introduces the principles of two-stage case-control design.its implementing steps in genome-wide associmion study and the features of its application. Thc method is illustrated with an example. |
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