辽宁省大棚作业农民慢性阻塞性肺疾病危险因素分析

刘朔; 李丽云; 李振华; 闻德亮; 王笑歌

文章摘要

刘朔,李丽云,李振华,闻德亮,王笑歌.辽宁省大棚作业农民慢性阻塞性肺疾病危险因素分析[J].中华流行病学杂志,2012,33(3):280-285

辽宁省大棚作业农民慢性阻塞性肺疾病危险因素分析

Risk factors on chronic obstructive pulmonary disease among greenhouse workers in Liaoning province

收稿日期:2011-10-24 出版日期:2014-09-09

DOI：

中文关键词: 慢性阻塞性肺疾病危险因素大棚作业

英文关键词: Chronic obstructive pulmonary disease Risk factors Greenhouse workers

基金项目:”十一五”国家科技支撑计划(2007BAI24B04);中华医学会基金(07010320040,08020680146);辽宁省教育厅基金(2009A760)

作者	单位	E-mail
刘朔	中国医科大学附属第四医院呼吸内科, 沈阳 110032
李丽云	中国医科大学附属第一医院感染科
李振华	中国医科大学校部呼吸内科
闻德亮	中国医科大学校部	cmu_vip@126.com
王笑歌	中国医科大学附属第四医院呼吸内科, 沈阳 110032	cm4hwxgn2005@126.com

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中文摘要:

目的探讨大棚作业人群慢性阻塞性肺疾病(COPD)患病危险因素.方法 2006-2009年采用随机、分层、整群抽样方法,对辽宁省800余个大棚从事作业的农民进行统一问卷调查、体格(血常规、血气分析、胸部X线及肺功能)检查,COPD确诊按照中华医学会呼吸病学分会制定的《慢性阻塞性肺疾病诊治指南》(2007年修订版)诊断标准.结果共调查从业人员5880人,有效应答者5420人,有效应答率92.18％.年龄(x²＝32.530,P=0.000)、棚内日劳作时间(x²=21.311,P=0.000)、大棚通风频率(x²=9.79l,P=0.007)及大棚面积(x²=73.645,P=0.000)危险因素存在地区差异.logistic回归分析提示,吸烟(OR=1.976,95％CI:1.672～2.334)、年龄(OR=4.188,95％CI:3.718 ～ 4.718)、菌棚(相对于蔬菜棚,OR=1.302,95％CI:1.016 ～ 1.669)、花卉棚(相对于蔬菜棚,OR=1.503,95％CI:1.201～1.880)为大棚作业农民COPD的危险因素；从业年限(OR=0.684,95％CI:0.609 ～ 0.767)是大棚作业农民COPD的保护因素.结论辽宁省大棚作业农民COPD的发生与多种因素相关,应重视其防治.

英文摘要:

Objective To study the risk factors of chronic obstructive pulmonary disease (COPD) among greenhouse farmers in Liaoning province.Methods According to geographical differences in Liaoning province,stratified-cluster-random sampling method was used.A total of 5420 greenhouse farmers working in more than 800 greenhouses were investigated with unified questionnaire,physical examination,blood routine examination,blood gas analysis,chest X-ray and pulmonary function tests.Diagnosis of COPD was made according to the criteria for "chronic obstructive pulmonary disease of diagnosis and treatment guidelines" (2007 revision) by the Chinese Respiratory Disease Society.Results The total number of farmers under study was 5880,including 5420 respondants(92.18％) with effective data.Risk factors were found on age(x²＝32.530,P=0.000),time working in greenhouses every day ( x²=21.311,P =0.000 ),frequency of ventilation ( x²=9.791,P=0.007) and the location of the greenhouses(x²=73.645,P=0.000).When using SPSS 17.0 for the single factor logistic regression analysis,results indicated that smoking(OR＝1.976,95％CI:1.672-2.334),age ( OR =4.188,95 ％ CI:3.718-4.718 ),greenhouses for fungus ( compared with vegetables,OR=1.302,95％CI:1.016-1.669),flowers and plants (compared with vegetables greenhouses,OR=1.503,95％ CI:1.201-1.880) were the risk factors of COPD among greenhouse farmers while the protective factor was the years of working in the greenhouse (OR=0.684,95％ CI:0.609-0.767).Conclusion The overall morbidity of COPD among greenhouse farmers in Liaoning province was 17.47％ with various risk factors.

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