文章摘要
朱士玉,后永春,舒文,张国良,聂绍发,陈伟,成诗明,许奕华.中国四省市结核病发病危险因素研究[J].中华流行病学杂志,2013,34(2):129-132
中国四省市结核病发病危险因素研究
Study Oil the risk factors of tuberculosis in four cities and provirices in China
收稿日期:2012-08-04  出版日期:2014-08-07
DOI:10.3760/cma.j.issn.0254-6450.2013.02.005
中文关键词: 结核病;危险因素;病例对照研究
英文关键词: Tuberculosis;Risk factors;Case.control study
基金项目:国家科技重大专项结核病预警模式研究(2008ZXl0003-008)
作者单位E-mail
朱士玉 430030 武汉,华中科技大学同济医学院公共卫生学院流行病与卫生统计学系  
后永春 430030 武汉,华中科技大学同济医学院公共卫生学院流行病与卫生统计学系  
舒文 430030 武汉,华中科技大学同济医学院公共卫生学院流行病与卫生统计学系  
张国良 430030 武汉,华中科技大学同济医学院公共卫生学院流行病与卫生统计学系  
聂绍发 430030 武汉,华中科技大学同济医学院公共卫生学院流行病与卫生统计学系  
陈伟 中国疾病预防控制中心结核病控制中心  
成诗明 中国疾病预防控制中心结核病控制中心  
许奕华 430030 武汉,华中科技大学同济医学院公共卫生学院流行病与卫生统计学系 xuyihua-6@hotmail.com 
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中文摘要:
      目的探讨中国东、中部广东、湖南、江苏、上海四省市结核病发病的影响因素,为结核病防控工作提供参考依据。方法2009年11月-2011年2月,采用结核病发病监测户卡对四省市若干乡镇/街道的常住人口,共进行3次以全人群为基础的入户调查。调查中的474例结核病患者作为病例组,从源人群中按地区、年龄、性别进行频数匹配,随机抽取1896位非结核病患者作为对照组,进行发病危险因素的病例对照研究。资料分析采用单因素和多因素非条件logistic回归分析。结果多因素分析结果提示,结核病史(OR=52.356,95%CI:18.956~144.607)、人均居住面积≥50 m2(OR=8.742,95%CI:1.107~69.064)、结核病患者接触史(OR-6.083,95%CI:2.336~15.839)、外来人口(OR=3.306,95%CI:1.907~5.734)是结核病发生的危险因素,文化程度高(OR=O.284,95%CI:0.110~0.733)是其保护因素。结论加强对既往有结核病史者、结核病接触者以及外来人口的结核病管理控制工作,将有助于降低结核病的流行强度。
英文摘要:
      0bjective To investigate the influencing factors on tuberculosis(TB)in four provinces in the eastern and eentral parts of China.Methods From Nov.2009 to Feb.20 11.three population-based field surveys were conducted among the resident population in several townships/streets in Guangdong,Hunan and Jiangsu provinces and Shanghai municipality to collect TB-related information.474 sputum smear positive TB patients and 1 896 controls were randomly selected from the population under study and each case was matched by province,age and sex using a frequency matching method.Single.vailable and multiple non-conditional logistic regression modeling were applied for data analysis。and odds ratios(ORs)and their corresponding 95%confidence intervals (CIs)were estimated.Results Data from Single-vailable analysis showed that TB history,history of exposure to TB,DM history,immigrant population and per-capita living space were risk factors for TB.and high level of education was protective factors.Results from multiple logistic regression showed that the risk factors ofTB would include the following items:history ofhaving had TB(OR=52.356.95%CI:18.956-144.607),living space over 50 m2 per-capita(0R=8.742,95%CI:1.107-69.064)。history ofexposuretoTB(0R=6.083,95%CI:2.336-15 839)andbeingimmigrants(OR=3.306,95%CI:1.907-5.734),while having had high degree of education as the protective factor ofTB(OR=O.284.95%CI:0.110一0.733).Conclusion Control programs targeting those everhaving TB patients and contacts to TB patients as well as immigrants should be strengthened.
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