文章摘要
王耕,李立明,胡永华,詹思延,吕筠,高文静,余灿清,王胜锋,曹卫华,王瑾.上海市社区人群高血压危险因素聚集与患病关系的研究[J].中华流行病学杂志,2013,34(4):307-310
上海市社区人群高血压危险因素聚集与患病关系的研究
Relationship between the clustering of risk factors and the prevalence of hypertension in the community residents living in Shanghai
收稿日期:2013-01-08  出版日期:2014-09-03
DOI:
中文关键词: 高血压;危险因素;聚集
英文关键词: Hypertension;Risk factor;Cluster
基金项目:国家“十一五”科技支撑计划(2006BAl01A01)
作者单位E-mail
王耕  caoweihua60@163.com 
李立明  lmlee@pumc.edu.cn 
胡永华   
詹思延   
吕筠   
高文静   
余灿清   
王胜锋   
曹卫华   
王瑾  caoweihua60@163.com 
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中文摘要:
      目的 <\b>研究超重与中心型肥胖、家族遗传史、不适量饮酒、吸烟、血脂异常和高血糖6项危险因素的聚集与高血压患病间的关系.方法 <\b>利用2008-2011年对15 158名35 ~ 74岁上海市社区居民进行的心脑血管疾病社区综合防治研究项目数据,采用单因素和多因素统计方法,描述危险因素聚集与高血压之间的相关性,使用纵向队列进一步对因果关系进行探讨.结果 <\b>基线调查高血压总现患率为41.9%.随着高血压危险因素聚集数目的增加,与高血压患病关联的OR值(按年龄调整)增大.聚集数目为1~5项及以上的男性其OR值依次为3.157 (95%CI:2.152 ~ 4.630)、6.428 (95%CI:4.435 ~ 9.319)、11.797 (95%CI:8.135~ 17.105)、19.723 (95%CI:13.414 ~ 29.000)、33.051 (95% CI:21.449~50.930),聚集数目为1~4项的女性其OR值依次为2.917 (95%CI:2.374~ 3.585)、6.499 (95%CI:5.307~ 7.959)、15.717 (95%CI:12.609~ 19.591)、31.719(95%CI:21.744~ 46.270).在纵向队列中,男性和女性的2年发病率分别为1.9%和1.6%.同无危险因素人群相比,聚集数目较多的人群2年发病率较高,女性中当聚集数目为2及3项时其RR值分别为2.111(95%CI:1.024 ~ 4.350)、3.000(95%CI:1.287 ~ 6.995),差异有统计学意义.结论 <\b>随着危险因素聚集数目的增加,高血压患病风险升高,应对危险因素进行综合防控.
英文摘要:
      Objective <\b>To study the association between the clustering manifestation of factors as overweight and central obesity,family heredity,immoderate alcohol drinking,tobacco smoking,hypedipidemia,hyperglycemia and the prevalence of hypertension.Methods <\b>Data was from a program related to the comprehensive prevention and control strategies on cardiac-cerebral vascular disease carried out in the communities of Shanghai,to describe the relationship between the clustering of risk factors and hypertension.This program included 15 158 people with complete data at the age of 35-74,from 2008-2011.Both single factor and multi-factor analysis were used and longitudinal study was performed to further explore the causal relationship.Results <\b>The overall prevalence of hypertension at the baseline survey was 41.9%.The associated ORs (age-adjusted) of hypertension parallelly increased with the number of risk factors under clustering.The associated OR of the males with 1,2,3,4 as well as 5 and above risk factors were 3.157 [95% confidence interval (CI):2.152-4.630],6.428 (95%CI:4.435-9.319),11.797 (95%CI:8.135-17.105),19.723 (95% CI:13.414-29.000),33.051 (95%CI:21.449-50.930) respectively.In females with 1,2,3 as well as 4 risk factors,the associated ORs were 2.917 (95%CI:2.374-3.585),6.499 (95%CI:5.307-7.959),15.717(95%CI:12.609-19.591) and 31.719 (95%CI:21.744-46.270),respectively.For longitudinal study,the 2-year incidence of hypertension in males and females were 1.9% and 1.6%,respectively.Compared to those people without risk factors,the incidence was higher in the people with a larger number of clustering.When the clustering number reaching 2 or 3 in females,the relative risk (RR) were 2.111 (95%CI:1.024-4.350) and 3.000 (95% CI:1.287-6.995) respectively,with statistically significant difference.Conclusion <\b>The risk of hypertension parallelly increased with the clustering number of relevant risk factors.Comprehensive prevention and control on related risk factors was required.
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