文章摘要
李婧,马晓萍,于春梅,欧文静,张盟思,梁庆成,赵景波.睡眠时间与脑梗死关系的病例对照研究[J].中华流行病学杂志,2013,34(9):914-916
睡眠时间与脑梗死关系的病例对照研究
A ease-control study on the duration of sleeping and cerebral infarction
收稿日期:2013-04-01  出版日期:2014-09-03
DOI:
中文关键词: 脑梗死|睡眠不足|病例对照研究
英文关键词: Cerebral infarction|Short sleep duration|Case-control study
基金项目:黑龙江省自然基金(D201235)
作者单位E-mail
李婧 150081 哈尔滨医科大学公共卫生学院  
马晓萍 150081 哈尔滨医科大学公共卫生学院  
于春梅 北京市垂杨柳医院综合乳腺科  
欧文静 150081 哈尔滨医科大学公共卫生学院  
张盟思 150081 哈尔滨医科大学公共卫生学院  
梁庆成 哈尔滨医科大学附属第二医院神经内  
赵景波 150081 哈尔滨医科大学公共卫生学院 zhaojbl68@sina.Com 
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中文摘要:
      目的 探讨睡眠时间与脑梗死的关系。方法 采用病例对照研究方法选择2011年12月至2012年12月哈尔滨医科大学第二附属医院1037例脑梗死住院患者作为病例组,以同期健康体检的1205名非脑血管病者作为对照组,采用统一的调查问卷。数据分析采用χ2、u检验和多 因素非条件logistic回归模型。结果 以睡眠时间6~8 h者为基准相比,调整年龄、性别、BMI、腰臀围比值、吸烟、饮酒、高血压、糖尿病、冠心病以及血脂指标后,睡眠时间<6 h者患脑梗死的风险增加(OR=2.81,95%CI:1.68~4.70);睡眠时间>8 h者与脑梗死无关联(OR=O.76,95%CI:0.48~1.20)。按照性别分层后,睡眠时间<6 h与脑梗死的相关性仍然存在,且女性睡眠时间<6 h者脑梗死发生风险高于男性,OR值分别为5.58(95%CI:1.78~17.52)、2.00(95%CI:1.10~3.64)。结论 睡眠不足可能是脑梗死的危险因素。
英文摘要:
      0bjective To explore the relationship between duration of sleeping and cerebral infarction.Methods A case-control study involved 1037 cerebralinfarction patients admitted by the Second Affiliated Hospital of Harbin Medical University,December 201l-December 2012 as cases. Another 1205 adults free from cerebro-vascular diseases who had undergone physical examination in the hospital at the same period.were served as controls.All the subjects were interviewed with unified questionnaire.Chi-square test,u-test and multivariate logistic regression analysis were performed. Results Atier adjustment for potential confounding factors including age,sex,bodv mass index, wrist-hip ratio,smoking,alcoholintake,hypertension,diabetes mellitus,coronary artery disease and lipid parameters,data from the multivariate logistic regression analysis showed that the risk of cerebral infarction was greater in people who slept less than 6 hours per night than those who slept between 6 hours and 8 hours per night,with an odds ratio(95%CI)as 2.81(95%CI:1.68-4.70). There was no significant association between factor as‘sleeping longer than 8 hours/pre day’and cerebralinfarction.Through the subgroup analysis.data showed that the association between‘shorter than 6 hour sleep/night’and cerebral infarction consistently exsited,across the categories of sex.and the degree of association was greater in women than in men,with the odds ratio as 5.58(95%CI:1.78-17.52)and 2.00(95%CI:1.10-3.64)respectively.iConclusion Short sleeping duration might increase the risk of developing cerebral infarction.
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