| 李婧,马晓萍,于春梅,欧文静,张盟思,梁庆成,赵景波.睡眠时间与脑梗死关系的病例对照研究[J].中华流行病学杂志,2013,34(9):914-916 |
| 睡眠时间与脑梗死关系的病例对照研究 |
| A ease-control study on the duration of sleeping and cerebral infarction |
| 收稿日期:2013-04-01 出版日期:2014-09-03 |
| DOI： |
| 中文关键词: 脑梗死|睡眠不足|病例对照研究 |
| 英文关键词: Cerebral infarction|Short sleep duration|Case-control study |
| 基金项目:黑龙江省自然基金(D201235) |
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| 中文摘要: |
| 目的 探讨睡眠时间与脑梗死的关系。方法 采用病例对照研究方法选择2011年12月至2012年12月哈尔滨医科大学第二附属医院1037例脑梗死住院患者作为病例组，以同期健康体检的1205名非脑血管病者作为对照组，采用统一的调查问卷。数据分析采用χ2、u检验和多 因素非条件logistic回归模型。结果 以睡眠时间6～8 h者为基准相比，调整年龄、性别、BMI、腰臀围比值、吸烟、饮酒、高血压、糖尿病、冠心病以及血脂指标后，睡眠时间＜6 h者患脑梗死的风险增加(OR=2．81，95％CI：1．68～4．70)；睡眠时间＞8 h者与脑梗死无关联(OR=O．76，95％CI：0．48～1．20)。按照性别分层后，睡眠时间＜6 h与脑梗死的相关性仍然存在，且女性睡眠时间＜6 h者脑梗死发生风险高于男性，OR值分别为5．58(95％CI：1．78～17．52)、2．00(95％CI：1．10～3．64)。结论 睡眠不足可能是脑梗死的危险因素。 |
| 英文摘要: |
| 0bjective To explore the relationship between duration of sleeping and cerebral infarction．Methods A case-control study involved 1037 cerebralinfarction patients admitted by the Second Affiliated Hospital of Harbin Medical University，December 201l-December 2012 as cases． Another 1205 adults free from cerebro-vascular diseases who had undergone physical examination in the hospital at the same period．were served as controls．All the subjects were interviewed with unified questionnaire．Chi-square test，u-test and multivariate logistic regression analysis were performed． Results Atier adjustment for potential confounding factors including age，sex，bodv mass index， wrist-hip ratio，smoking，alcoholintake，hypertension，diabetes mellitus，coronary artery disease and lipid parameters，data from the multivariate logistic regression analysis showed that the risk of cerebral infarction was greater in people who slept less than 6 hours per night than those who slept between 6 hours and 8 hours per night，with an odds ratio(95％CI)as 2．81(95％CI：1．68-4．70)． There was no significant association between factor as‘sleeping longer than 8 hours／pre day’and cerebralinfarction．Through the subgroup analysis．data showed that the association between‘shorter than 6 hour sleep／night’and cerebral infarction consistently exsited，across the categories of sex．and the degree of association was greater in women than in men，with the odds ratio as 5．58(95％CI：1．78-17．52)and 2．00(95％CI：1．10-3．64)respectively．iConclusion Short sleeping duration might increase the risk of developing cerebral infarction． |
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