| 董燕,钟朝晖,李红,李杰,王应雄,彭斌,张茂忠,黄巧,闫菊,徐飞龙.重庆市O～5岁儿童出生缺陷空间地理分布 及其与土壤化学元素关系的研究[J].中华流行病学杂志,2013,34(10):975-979 |
| 重庆市O～5岁儿童出生缺陷空间地理分布 及其与土壤化学元素关系的研究 |
| Spatial distribution of birth defects among children aged 0 to 5 years and its relationship with soil chemical elements in Chongqing |
| 收稿日期:2013-06-12 出版日期:2014-10-08 |
| DOI：10．3760/cma．j．issn．0254—6450．2013．10．008 |
| 中文关键词: 出生缺陷|土壤|化学元素|地理信息系统|空间分布 |
| 英文关键词: Birth defect|Soil|,Chemical elements|Geographic information system|Spatial distribution |
| 基金项目:重庆市科技攻关计划(201199c503)；重庆市人口和计划生育科学技术研究院资助项目(渝人计研发[2010122号) |
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| 中文摘要: |
| 目的探讨出生缺陷发生率与土壤化学元素含量的相关性，为筛选致病因子及其防 治提供科学依据。方法用Maplnfo 7．0软件绘制33个研究区出生缺陷发生率和11种土壤化学 元素含量水平的空间分布地图，将两变量地图叠加进行空间相关性分析；采用SAS 8．0软件做两 者的单因子、多因子及主成分分析，并综合评价两者的关联程度。结果 出生缺陷发生率空间分 布图与土壤化学元素铜(Cu)、铬(Cr)、碘(I)、硒(Se)、锌(zn)含量异常的分布图呈一定程度的负 相关，与铅(Pb)含量水平呈一定程度正相关；主成分回归方程提示：Cu(0．002)、砷(As)(一0．07)、镉 (Cd)(o．05)、Cr(一0．001)、Zn(0．001)、I(一0．03)、Pb(O．08)、氟(F)(一o．002)元素含量的高低可能是影 响出生缺陷患病率的重要因素。结论出生缺陷发生率与土壤中Cu、Cr、I、Se、zn、Pb的含量水平 在空间地理分布上具有相关性，其中元素Cr、I、Pb可能是出生缺陷发生的原因之一。 |
| 英文摘要: |
| Objective To explore the correlation between the incidence of birth defects and the contents of soil elements SO as to provide a scientific basis for screening the related pathogenic factors that inducing birth defects for the development of related preventive and conlTol strategies． Methads Maplnfo 7．0 software was used to draw the maDs on spatial distribution regarding the incidence rates of birth defects and the contents of 1l chemical elements in soilin the 33 studied areas． Variables on the two maDs were superposed for analyzing the spatial correlation．SAS 8．0 software was used to analyze single factor．multi．factors and principal components as well as to comprehensively evaluate the degrees of relevance．Results Different incidence rates of birth defects showed in the maps of spatial distribution presented certain degrees of negative correlation with anomalies of soil chemical elements，including copper，chrome，iodine，selenium，zinc while positively correlated with the 1evels of lcad．Results from the principal component regression equation indicating thatthe contents ofcopper(0．002)，arsenic(-0．07)，cadmium(0．05)，chrome(-0．001)，zinc(0．001)，iodine(-0．03)，lead(0．08)，fluorine(-0．002)might serve as important factors that related to the prevalence of birth defects．Conclusion Through the study on spatial distribution，we noticed that the incidence rates of birth defes were related to the contents of copper，chrome，iodine， selenium．zinc，lead in soil while the contents of chrome，iodine and lcad might lcad to the occurrence ofbirth defects． |
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