文章摘要
罗胜兰,胡如英,龚巍巍,王浩,潘劲费,方荣,俞敏.浙江省2005-2010年结直肠癌生存率分析[J].中华流行病学杂志,2013,34(12):1194-1197
浙江省2005-2010年结直肠癌生存率分析
Survival rate of colorectal cancer patients during 2005-2010 in Zhejiang province,China
收稿日期:2013-07-15  出版日期:2014-10-16
DOI:10.3760/cmaj.issn.0254-6450.2013.012.009
中文关键词: 结直肠癌  生存率  流行病学
英文关键词: Colorectal cancer  Survival rate  Epidemiology
基金项目:
作者单位E-mail
罗胜兰 315211 宁波大学医学院预防医学系  
胡如英 浙江省疾病预防控制中心  
龚巍巍 浙江省疾病预防控制中心  
王浩 浙江省疾病预防控制中心  
潘劲费 浙江省疾病预防控制中心  
方荣 浙江省疾病预防控制中心  
俞敏 浙江省疾病预防控制中心 myu@cdc.zj.cn 
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中文摘要:
      目的分析2005—2010年浙江省30个卫生监测区全人群结直肠癌患者的生存率。方法随访浙江省卫生监测区2005—2010年17 235例结直肠癌患者的生存情况,生存时间计算截至2012年12月31日,利用SURV 3.01软件计算观察生存率(OS)及相对生存率(RS)。结果结直肠癌患者1、3、5年OS分别为76.71%、58.14%、50.58%,RS为78.93%、63.48%、58.73%。其中男性RS为79.36%、63.63%、58.85%;女性RS为78.35%、63.29%、58.57%,男女性生存率差异无统计学意义(X2=1.08,P=0.298)。城市地区5年OS和RS分别为55.06%与64.09%,高于农村地区的47.59%和55.16%,差异有统计学意义(X2=85.84,P2=333.42,P<0.001)。结肠癌与直肠癌5年Rs分别为61.47%和56.45%,结肠癌患者中长期Rs高于直肠癌患者(X2=7.26,P<0.05)。结论浙江省结直肠癌生存率存在地区差异,公共卫生资源应向农村地区倾斜;影响<55岁结直肠癌患者生存率的因素有待进一步研究。
英文摘要:
      Objective To analyze the survival rate of colorectal cancer,using data from thepopulation—based cancer registry during 2005-2010 in Zhejiang.Methods The 1ast follow-uDactivites on 1 7 235 Cases regarding the survival status was December 3 1.20 1 2.Both cumulativeobserved survival rate(OS)and relative survival rate(RS)were calculated with SURV 3.01 softwaredrawn uD bV Hakulinen.Results The OS on 1,3 and 5 year were 76.71%,58.14%,50.58%and theRS on 1,3 and 5 year were 78.93%,63.48%,58.73%,respectively.The 1,3 and 5 year relativesurvival rates on males US.females were 79.36%VS.78.35%,63.63%VS.63.29%,and 58.85%VS.58.57%.respectively and the difierence between them was not statistically significant(x2=1.08,P=0.298).The 5 year 0S and RS of the urban population were 55.06%and 64.09%and the 5 year OSand RS ofthe rural population were 47.59%and 55.16%,with statistically significant differences(x2=85.84.P<0.001).The 55-64 age group appeared higher relative survival rate.There were significantdifferences in the survival rates among different age groups(x2=333.42,P<0.001).The 5 year RS ofcolon VS.rectum were 61.47%VS.56.45%.Colon patients showed better relative survival rate(x2=7.26.P<0.05).Conelusion The wide variations in colorectal cancer survival rates were seenbetween the urball and Vllral populations.Public health resources should be focused on D.n'al areas.Patients younger than 55 years should be under specific attention to further understand the relatedfactors which influencing the prognosis of the diseases.
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