| 詹军,马江涛,陈慧,袁芳,马学旻,刘翔,郝琼.宁夏地区2011 年病毒性腹泻病例病原学研究[J].中华流行病学杂志,2014,35(6):729-732 |
| 宁夏地区2011 年病毒性腹泻病例病原学研究 |
| Etiological study on cases with viral diarrhea in Ningxia during 2011 |
| 收稿日期:2013-11-28 出版日期:2014-09-02 |
| DOI： |
| 中文关键词: 病毒性腹泻 轮状病毒 杯状病毒 星状病毒 肠道腺病毒 |
| 英文关键词: Viral diarrhea Human rotavirus Human calicivirus Human astrovirus Human enteral adenovirus |
| 基金项目:宁夏自然科学基金项目（NZ13219）;宁夏卫生厅重点科研计划课题（2012040） |
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| 中文摘要: |
| 目的 了解2011 年宁夏地区腹泻病例中轮状病毒（HRV）、杯状病毒（HuCV）、星状病毒（HAstV）及肠道腺病毒（HAdV）感染情况。方法 2011 年收集宁夏不同地区腹泻病例的粪便标本，采用ELISA 法检测A组HRV，阳性标本采用RT-PCR 法进行分型鉴定;采用RT-PCR 或PCR法检测HuCV、HAstV和HAdV。结果 共收集腹泻病例粪便标本690 份，其中HRV占2.17%（15/690）、HuCV 占21.74%（150/690）、HAstV 占3.19%（22/690）、HAdv 占6.52%（45/690）、混合感染占4.20%（29/690）。15 份HRV G血清型与P基因型以G1、G3、P［4］型为优势株。结论 2011 年宁夏地区病毒性腹泻主要以＜2 岁婴幼儿为主，HuCV是主要病原体。 |
| 英文摘要: |
| Objective To investigate the etiological characteristics of human rotavirus （HRV），human calicivirus （HuCV），human astrovirus （HAstV） and human enteral adenovirus （HAdV）in Ningxia province during 2011. Methods Stool specimen was collected from acute diarrhea case of Ningxia during 2011. HRV was detected by ELISA and serotype/genotype identified on those RT-PCR positive specimens. HuCV，HAstV and HAdV were detected by RT-PCR. Results In this study，a total of 690 specimens were detected，with the infection rates of HRV，HuCV，HAstV and HAdV as 2.17%，21.74%，3.19% and 6.52%，respectively. Co-infections were found in 4.20% of all the samples being tested. Among 15 HRV positive cases，serotypes G1，G3 and P［4］were the most predominant strains. Conclusion Children who were under 2 years of age were the majority among patients infected by diarrhea viruses while HuCV was recognized as the main pathogen responsible for the viral diarrhea casses in Ningxia，2011. |
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