| 李洁,杨文杰,王哲.河南省2008-2013年15岁以下儿童丙型肝炎流行特征分析[J].中华流行病学杂志,2014,35(10):1119-1122 |
| 河南省2008-2013年15岁以下儿童丙型肝炎流行特征分析 |
| Epidemiological characteristics of HCV infected children under 15 years of age,in Henan province from 2008 to 2013 |
| 收稿日期:2014-04-10 出版日期:2014-09-15 |
| DOI：10.3760/cma.j.issn.0254-6450.2014.10.009 |
| 中文关键词: 丙型肝炎 儿童 报告病例数 报告发病率 |
| 英文关键词: Hepatitis C Children Reported cases Reported incidence |
| 基金项目:国家“十二五”科技重大专项（2012ZX10004905） |
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| 中文摘要: |
| 目的 描述河南省15 岁以下儿童丙型肝炎（丙肝）流行特征及变化趋势。方法 收集2008-2013 年河南省丙肝报告病例资料，对其流行特征进行分析。结果 河南省儿童丙肝报告病例数及发病率2008-2012 年间逐年增加，2013 年有所下降。报告发病率从2008 年的2.37/10 万上升至2012 年的3.23/10 万，2013 年下降至1.77/10 万。女童报告病例数逐年增多。0～1 岁组病例报告较为集中，但构成比逐年下降。发病率较高的地区集中在郑州等大城市，省内流动人口报告病例的构成比从2008 年的49.02%上升到2013 年的59.77%。发病与诊断时间间隔逐年增大，2008-2013 年M和四分位数间距（IQR）分别为0（0～2）、0（0～2）、1（0～2）、1（0～3）、1（0～5）、1（0～3）d。结论 河南省儿童丙肝发病率逐年增高，同时显现省内病例流动性增大、发病与诊断时间间隔增大的趋势。 |
| 英文摘要: |
| Objective To describe the epidemiological characteristics and changing trend of HCV-related children in Henan province. Methods Data was analyzed based on the case-reporting records on hepatitis C from 2008 to 2013. Results The number of reported cases and incidence of HCV-related children had increased annually from 2008 to 2012. The reported incidence on HCV-related children increased from 2.37 per 100 000 in 2008,to 3.23 per 100 000 in 2012,but it decreased to 1.77 per 100 000 in 2013. Reported cases on females increased annually. The 0-1 age group had the largest proportion but it decreased annually. Large cities as Zhengzhou,had high incidence,and the mobile population within the province also showed an annual increase,from 49.02% in 2008,to 59.77% in 2013. Time between onset and diagnosis（days）of the disease increased and the M and IQR from 2008 to 2013 appeared as 0（0-2）,0（0-2）,1（0-2）,1（0-3）,1（0-5） and 1（0-3）. Conclusion The incidence of HCV-related children in Henan province showed an annual increase,along with the increasing trend of mobile population in the province as well as the longer time span between onset and diagnosis of the disease. It is suggested that strengthening the program on monitor,as well as on effective prevention and control measures be in place accordingly. Targets should also be focused on pregnant women,migrants,other key groups,so as to better perform on early detection and treatment. |
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