| 邬辉,王建跃,仝振东,唐安,任飞林,叶凌,王承维.浙江省舟山市2011－2013年发热伴血小板减少综合征流行特征分析[J].中华流行病学杂志,2014,35(12):1371-1374 |
| 浙江省舟山市2011－2013年发热伴血小板减少综合征流行特征分析 |
| Epidemiological characteristics of severe fever with thrombocytopenia syndrome in Zhoushan,Zhejiang,2011-2013 |
| 收稿日期:2014-07-15 出版日期:2014-12-10 |
| DOI：10.3760/cma.j.issn.0254-6450.2014.12.013 |
| 中文关键词: 发热伴血小板减少综合征 新布尼亚病毒 流行病学 |
| 英文关键词: Severe fever with thrombocytopenia syndrome Severe fever with thrombocytopenia syndrome Bunyavirus Epidemiology |
| 基金项目:浙江省公益技术研究社会发展项目(2013C33116) |
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| 中文摘要: |
| 目的 分析浙江省舟山市2011－2013年发热伴血小板减少综合征(SFTS)病例的流行特征,为防控提供建议和对策.方法 收集整理舟山市2011－2013年SFTS病例个案调查表及人口学资料,利用描述性流行病学方法分析病例临床和流行病学特征.结果 2011－2013年舟山市共报告SFTS 45例,病死率为11.11%(5/45),其中岱山县41例(91.11%).病例以山区丘陵>50岁人群为主(93.33%),5－7月为发病高峰(84.44%),多数为农民(42.22%)和家务待业(31.11%),男女性发病率差异无统计学意义(P>0.05).大部分病例有发热(97.78%)、食欲减退(91.11%)、乏力(62.22%)、畏寒(44.44%)等非特异性临床表现,且均伴有血小板、白细胞水平进行性下降.病例居住地环境卫生普遍较差,且病前2周进行农田种植等户外活动的比例为68.89%(31/45),部分病例发病前有明确蜱叮咬史,并发现3起流行病学相关事件.结论 舟山市SFTS是由新布尼亚病毒感染引起,具有清晰流行病学特征的自然疫源性疾病,蜱为主要的传播媒介,且可能存在人传人现象.改善居住环境卫生条件及做好户外防护措施对降低发病具有一定意义. |
| 英文摘要: |
| Objective To analyze the epidemiological characteristics of severe fever cases,with thrombocytopenia syndrome (SFTS) in Zhoushan,Zhejiang,2011-2013 and to provide evidence for the development of related strategies for prevention and control of the disease. Methods Data was collected from the studies and related demography of the cases with SFTS in Zhoushan,2011-2013. Clinical and epidemiological characteristics of the cases with SFTS were analyzed descriptively. Results During 2011-2013,45 SFTS cases were reported in Zhoushan city,with fatality rate as 11.11% (5/45),including 41 cases (91.11%) reported in Daishan county. Most cases aged 50 or over,residing in hilly regions (93.33%). The epidemic peak was seen from May to July (84.44%). Incidence rates of the disease did not show significant statistical differences between males and females. Most cases were farmers (42.22%) and housewives (31.11%). Most patients complained of fever(97.78%),anorexia(91.11%),fatigue(62.22%),chill(44.44%) and other non-specific clinical manifestations but all appeared progressive thrombocytopenia and leucopenia. Sanitation condition of the patients was generally poor. 68.89%(31/45) of cases had farmed,mowed or involved in other outdoor activities in the previous two weeks,with some of them reported having exposed to tick bites. Three events were reported,epidemiologically. Conclusion SFTS in Zhoushan was a infectious disease with natural foci and caused by SFTSV. Ticks might serve as the main vectors for SFTSV,and might cause direct transmission between humans. Improving the environment for living and carrying out essential protective measures in outdoor activities seemed to be significant in decreasing the incidence rate of the disease. |
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