| 葛增,张吉玉,陈晓荣,郭晓雷,颜流霞,唐俊利,蔡小宁,徐建伟,厚磊,马吉祥.山东省居民24小时尿钠钾比与代谢综合征的关系[J].中华流行病学杂志,2015,36(8):790-793 |
| 山东省居民24小时尿钠钾比与代谢综合征的关系 |
| Association between 24 h urinary sodium to potassium ratio and metabolic syndrome in Chinese adults |
| 收稿日期:2015-01-17 出版日期:2015-08-11 |
| DOI：10.3760/cma.j.issn.0254-6450.2015.08.004 |
| 中文关键词: 代谢综合征 24 h尿钠钾比 横断面研究 |
| 英文关键词: Metabolic syndrome Twenty-four hour urinary sodium to potassium ratio Cross-sectional study |
| 基金项目:山东省人民政府卫生部联合减盐防控高血压项目; 山东省科技发展计划(2012GSF11828) |
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| 中文摘要: |
| 目的 分析山东省居民24 h尿钠钾比与MS的关系。方法 2011年在山东省采用四阶段分层随机抽样方法抽取18~69岁居民作为研究对象, 测量其血糖、血脂四项、尿钠、尿钾和尿肌酐等指标。依据24 h尿钠钾比值将研究对象按照四分位数法分组, 采用二分类logistic分析钠钾比与MS的关系。结果 1 906名研究对象纳入分析, 其中男性1 003人, 女性903人。MS患病率为24.7%。经多因素logistic模型分析, 与24 h尿钠钾比值<4.3组相比, 4.3~5.6、5.7~8.1和≥8.1组MS患病风险OR值(95%CI)分别为1.27(0.93~1.71)、1.06(0.78~1.46)和1.45(1.06~1.97), 趋势检验显示, P<0.05。在MS各组分中, 中心性肥胖和血压升高风险与24 h尿钠钾比之间存在线性趋势(线性趋势检验P<0.05)。结论 随着24 h尿钠钾比增加, MS患病风险呈上升趋势。 |
| 英文摘要: |
| Objective To examine the association between 24 h urinary sodium to potassium ratio and metabolic syndrome (MS) in Chinese adults. Methods A population-based cross-sectional study was conducted among Chinese adults aged 18-69 years in Shandong province in 2011. Data on 24 h urinary excretion of sodium and potassium and components of MS were examined. Participants were divided into four groups according to the quartile of 24 h urinary sodium to potassium ratio. Results Of the 1 906 Chinese adults eligible for final data analysis, 471 (24.7%) were with MS. After completion of multivariate logistic regression analysis, when compared to the participants with 24 h urinary sodium to potassium ratio <4.3, the OR(95%CI) of participants with 24 h urinary sodium to potassium ratio during 4.3-5.6, 5.7-8.1, and ≥8.1 were 1.27(0.93-1.71), 1.06(0.78-1.46), and 1.45 (1.06-1.97), respectively (P values for linear trend <0.05). As for the components of MS, the odds of central obesity and elevated blood pressure but not the odds of elevated triglycerides, low high density lipoprotein cholesterol and elevated fasting glucose, had significantly increases with successive 24 h urinary sodium to potassium ratio quartiles (P values for linear trends <0.05). Conclusion The 24 h urinary sodium to potassium ratio appeared significantly associated with the odds of MS. |
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