| 郑山,蒲宏全,代敏,白亚娜,李海燕,昌盛,王敏珍,王正芳,朱锦兵,任晓卫,李娟生,程宁.金昌队列人群肺癌疾病负担研究[J].中华流行病学杂志,2016,37(3):311-315 |
| 金昌队列人群肺癌疾病负担研究 |
| Disease burden of lung cancer in Jinchang cohort |
| 收稿日期:2015-10-28 出版日期:2016-03-15 |
| DOI：10.3760/cma.j.issn.0254-6450.2016.03.003 |
| 中文关键词: 肺癌 死亡率 潜在减寿年 潜在工作损失年 直接经济负担 |
| 英文关键词: Lung cancer Mortality rate Potential yeas of life lost Working years of potential life lost Cohort |
| 基金项目:国家重大公共卫生服务项目(财社2012-64);金川集团股份有限公司科学技术项目(JKZ20120013) |
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| 中文摘要: |
| 目的 了解金昌队列人群中肺癌造成的疾病负担及其变化趋势。方法 采用历史队列研究方法,收集金昌队列人群 2001－2013年因肺癌而死亡的全部资料及2001－2010年肺癌住院患者的病案资料,应用死亡率、标化死亡率、直接经济负担、潜在减寿年(PYLL)、人均PYLL(APYLL)、潜在工作损失年(WPYLL)以及人均WPYLL(AWPYLL)等指标分析肺癌造成的疾病负担,运用Spearman秩相关和平均增长速度描述疾病负担的变化趋势。结果 2001－2013年金昌队列人群因肺癌死亡434例,粗死亡率为78.06/10万,年均增长速度为4.77%,呈逐年上升趋势。男性肺癌死亡率为108.90/10万,年均增长速度为4.24%,女性肺癌死亡率为26.08/10万,年均增长速度为6.91%。因肺癌而造成的PYLL和APYLL分别为3 723.71人年和8.58年。女性因肺癌造成的APYLL(15.94年)是男性(7.87年)的2.03倍。WPYLL和AWPYLL分别为1 161.00人年和2.68年,女性AWPYLL(5.63年)是男性(2.26年)的2.49倍。2001－2010年金昌队列人群肺癌住院患者人均直接经济负担为6 309.39元,无明显变化趋势。结论 肺癌对金昌队列人群造成沉重的疾病负担,是重要的健康问题。 |
| 英文摘要: |
| Objective To understand the current status of lung cancer disease burden in Jinchang cohort. Methods In this historical cohort study, the mortality data of the lung cancer from 2001 to 2013 and medical records of the lung cancer cases from 2001 to 2010 in Jinchang cohort were used, analyze mortality, direct economic burden, potential years of life lost (PYLL) and working PYLL(WPYLL) associated with lung cancer. Results A total of 434 lung cancer deaths occurred in Jinchang cohort from 2001 to 2013. The crude mortality rate of lung cancer was 78.06 per 100 000 from 2001 to 2013, with the increasing rate of 4.77%. The mortality rate of lung cancer in males and females were about 108.90 per 100 000 and 26.08 per 100 000 with the increasing rate of 4.24% and 6.91%, respectively. During the thirteen years, the PYLL and average PYLL (APYLL) of lung cancer were 3 721.71 person-years and 8.58 years. The APYLL of lung cancer in females (15.94 years) was higher than that in males (7.87 years). The WPYLL and the average WPYLL (AWPYLL) of lung cancer were 1 161.00 person-years and 2.68 years, respectively. The AWPYLL of lung cancer was also higher in females than in males. The direct economic burden of lung cancer from 2001 to 2010 in Jinchang cohort was 6 309.39 Yuan per case with no increased trend. Conclusion Lung cancer is the main health problem in Jinchang cohort, causing heavy disease burden. |
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