文章摘要
赵璇,程绍辉,郑敏娜,李龙,朱静瑾,宁铁林.病毒载量检测对HIV抗体确证实验结果不确定样本的辅助诊断研究[J].中华流行病学杂志,2016,37(7):992-995
病毒载量检测对HIV抗体确证实验结果不确定样本的辅助诊断研究
Study of auxiliary diagnostic value of viral load test for samples with indeterminate HIV antibody detection results
收稿日期:2016-01-21  出版日期:2016-07-15
DOI:10.3760/cma.j.issn.0254-6450.2016.07.017
中文关键词: 病毒载量  HIV抗体不确定  诊断
英文关键词: Viral load  Sample with indeterminate HIV detection result  Diagnosis
基金项目:天津市卫生行业重点攻关项目(14KG119)
作者单位E-mail
赵璇 300011 天津市疾病预防控制中心性病艾滋病预防控制所  
程绍辉 300011 天津市疾病预防控制中心性病艾滋病预防控制所 chengshaohui1972@163.com 
郑敏娜 300011 天津市疾病预防控制中心性病艾滋病预防控制所  
李龙 300011 天津市疾病预防控制中心性病艾滋病预防控制所  
朱静瑾 300011 天津市疾病预防控制中心性病艾滋病预防控制所  
宁铁林 300011 天津市疾病预防控制中心性病艾滋病预防控制所  
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中文摘要:
      目的 明确在HIV抗体确证实验结果不确定,又需及时诊断的情况下,病毒载量检测对诊断的辅助作用。方法 对2015年天津市MSM人群中32例HIV抗体确证实验结果为不确定的样本进行两次HIV病毒载量检测,并对该样本进行跟踪随访和确证实验,以证实其感染情况。结果 32例样本在HIV抗体确证实验结果不确定的情况下,两次病毒载量全部检测到数值,经随访抗体确证实验全部判为阳性。病毒载量检测结果与抗体确证实验结果相符。结论 病毒载量检测可以对窗口期感染者进行有效的辅助性诊断,可作为抗体确证实验结果不确定样本的辅助诊断依据。
英文摘要:
      Objective To evaluate the auxiliary diagnostic value of viral load test for samples with indeterminate HIV antibody detection results. Methods Thirty-two samples with indeterminate HIV antibody detection results collected from MSM were used for two viral load tests in Tianjin in 2015. Follow up was conducted for this population to confirm their HIV infection status. Results Virus loads were detected in the 2 viral load tests. In the follow-up survey, the results of HIV antibody test of all the samples were positive. The results of viral load test were completely consistent with those of HⅡV antibody confirmation test. Conclusion The viral load test was effective in the auxiliary diagnosis of HIV infection in window phase, which can be used for the samples with indeterminate HIV antibody detection results.
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