文章摘要
张周斌,薛振香,吴雪霁,王童敏,利耀辉,宋雪莲,晁先锋,王岗,乃孜班木·努尔麦麦提,阿依夏穆姑丽·巴吾顿,古丽巴哈·艾力亚斯,周自严,孙宝山,王玉忠,王鸣.新疆喀什地区维吾尔族糖尿病人群血脂异常及控制情况分析[J].中华流行病学杂志,2017,38(6):702-708
新疆喀什地区维吾尔族糖尿病人群血脂异常及控制情况分析
Prevalence of dyslipidemia and normal blood lipids level in Uygur population in Kashgar area of Xinjiang Uygur Autonomous Region
收稿日期:2016-12-21  出版日期:2017-06-19
DOI:10.3760/cma.j.issn.0254-6450.2017.06.003
中文关键词: 维吾尔族;糖尿病;血脂异常;控制率
英文关键词: Uygur;Diabetes,type 2;Dyslipidemia;Normal rate
基金项目:国家科技重大专项(2012ZX10004213005);广东省科技计划项目(2014A020209006);广州市医学重点学科建设项目(2017-2019-07)
作者单位E-mail
张周斌 510440 广州市疾病预防控制中心主任室  
薛振香 844100 喀什, 疏附县疾病预防控制中心免疫规划股  
吴雪霁 510440 广州市疾病预防控制中心基层公共卫生部  
王童敏 844100 喀什地区疾病预防控制中心免疫规划科  
利耀辉 510440 广州市疾病预防控制中心基层公共卫生部  
宋雪莲 844100 喀什, 疏附县疾病预防控制中心免疫规划股  
晁先锋 844100 喀什, 疏附县疾病预防控制中心免疫规划股  
王岗 844100 喀什, 疏附县卫生局  
乃孜班木·努尔麦麦提 844100 喀什, 疏附县疾病预防控制中心免疫规划股  
阿依夏穆姑丽·巴吾顿 844100 喀什, 疏附县疾病预防控制中心免疫规划股  
古丽巴哈·艾力亚斯 844100 喀什, 疏附县疾病预防控制中心免疫规划股  
周自严 510440 广州市疾病预防控制中心免疫规划部  
孙宝山 844100 喀什, 广东省对口支援新疆工作前方指挥部人事教育处
510060 广州, 广东省卫生和计划生育委员会疾病预防控制处 
 
王玉忠 844100 喀什, 疏附县卫生局  
王鸣 510440 广州市疾病预防控制中心主任室 wangming@gzcdc.org.cn 
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中文摘要:
      目的 了解新疆喀什地区维吾尔族糖尿病人群血脂异常及控制情况,为防治该地区糖尿病人群血脂紊乱提供依据。方法 采用分层整群随机抽样方法,对该地区5 078名18岁及以上的常住居民进行调查问卷、体格检查和实验室检测后,筛查糖尿病患者521例,描述其血脂异常以及各项血脂控制情况,分析造成血脂异常和影响血脂控制的因素。结果 糖尿病人群血脂代谢异常总患病率为59.50%(310/521),标化率为49.39%。65岁以上、超重、肥胖和腹部肥胖者发生血脂异常的风险分别增高0.771倍(95% CI:1.015~3.088)、1.132倍(95% CI:1.290~3.523)、1.688倍(95% CI:1.573~4.592)和0.801倍(95% CI:1.028~3.155)。和男性相比,女性是血脂异常的保护性因素,OR=0.507(95% CI:0.334~0.769)。TC、TG、HDL-C和LDL-C的总体控制率为11.13%。女性、BMI超标和腹部肥胖不利于血脂的总体控制。LDL-C的控制率随年龄、BMI和腰围的增大而降低(趋势检验χ2年龄=18.049,P<0.001;趋势检验χ2BMI=10.582, P=0.001;χ2腰围=19.081,P<0.001),随学历增高而增高(趋势检验χ2=9.764,P=0.002)。结论 该地区糖尿病人群血脂异常率处于较高水平,血脂总控制率则处于较低水平。肥胖是造成该地区糖尿病人群发生血脂异常的主要危险因素;女性在糖尿病血脂异常的防治中应该得到更多的重视。
英文摘要:
      Objective To understand the prevalence of dyslipidemia and normal blood lipids level in Uygur diabetes patients in Kashgar prefecture in southern area of Xinjiang. Methods A total of 5 078 local residents aged ≥ 18 years (42.56% were men) selected through cluster random sampling in Kashgar were surveyed by means of questionnaire survey, physical examination and laboratory test, and 521 diabetes patients were screened. Results The overall prevalence of dyslipidemia in diabetes patients was 59.50% (310/521) with adjusted rate as 49.39%. Age ≥ 65 years, overweight, obesity and abdominal obesity increased the risk for dyslipidemia by 0.771 times (95%CI:1.015-3.088), 1.132 times (95%CI:1.290-3.523), 1.688 times (95%CI:1.573-4.592) and 0.801 times (95%CI:1.028- 3.155) respectively. Compared with males, female was a protective factor for dyslipidemia (OR=0.507, 95%CI:0.334-0.769). The overall normal rate of blood lipids level including total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) for type 2 diabetes patients was 11.13%. Female, higher BMI and abdominal obesity were the factors influencing the overall normal blood lipids level. The normal rate of LDL-C level decreased with increase of age, BMI and waist circumferences (trend test χ2=18.049, P<0.001; trend test χ2=10.582, P=0.001; χ2=19.081, P<0.001), but increased with educational level (trend test χ2=9.764, P=0.002). Conclusion The prevalence of dyslipidemia in Uygur diabetes patients in Kashgar was high, however, the overall normal rate of blood lipid level was relatively low. Obesity was the most important risk factor for dyslipidemia in this area. More attention should be paid to dyslipidemia prevention in women.
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