| 吴小艳,李强,严惠,刘丹朦,高婧媛,赵亚玲.陕西省汉中市农村居民高血压与家族史的相关性分析[J].中华流行病学杂志,2017,38(8):1050-1054 |
| 陕西省汉中市农村居民高血压与家族史的相关性分析 |
| Association between family history and the risk of hypertension in rural districts of Hanzhong in Shaanxi province |
| 收稿日期:2016-12-10 出版日期:2017-08-12 |
| DOI：10.3760/cma.j.issn.0254-6450.2017.08.010 |
| 中文关键词: 高血压 家族史 农村居民 |
| 英文关键词: Hypertension Family history Rural residents |
| 基金项目:美国中华医学基金会（08-925） |
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| 中文摘要: |
| 目的 了解陕西省汉中市农村居民高血压患病情况，分析高血压患病与家族史的定量关系。方法 采用多阶段随机抽样方法，对汉中市农村居民进行高血压相关的问卷调查及身体测量，运用logistic回归模型分析家族史对高血压的影响。结果 共收集到2 817名18~80岁农村居民的完整资料，高血压粗患病率为33.7%。logistic回归分析显示，高血压家族史阳性者与阴性者相比，OR=2.06（95%CI：1.70~2.50）。一级亲属中高血压家族史的个体人数分别为1、2、3时其OR值（95%CI）分别为1.83（1.47~2.27）、2.94（2.09~4.13）、4.48（2.17~9.27）。女性人群中，父亲家族史阳性、母亲家族史阳性、父母家族史均为阳性时，OR值分别为2.50、1.61、2.82，均P<0.05。结论 家族史是高血压的危险因素，一级亲属中高血压家族史的个体人数与高血压患病呈剂量-反应关系，一级亲属中父亲、母亲高血压家族史可进一步影响高血压的发生。 |
| 英文摘要: |
| Objective To understand the prevalence of hypertension and quantitative relationship between family history and the risk of hypertension among rural residents living in Hanzhong District, Shaanxi province. Methods A multistage random sampling survey was conducted. Data on the characteristics related to hypertension were collected and physical examination was conducted. Logistic regression was used to analyze the relationship between family history and hypertension. Results A total number of 2 817 rural residents aged 18-80 with complete information were recruited. The crude prevalence of hypertension was 33.7%. Results from the logistic regression analysis showed that the OR was 2.06 (95%CI:1.70-2.50) between family histories with or without hypertension. When the first-degree relatives were with the degrees of family history of hypertention as Ⅰ, Ⅱ or Ⅲ, the OR values of hypertension appeared as 1.83 (95%CI:1.47-2.27), 2.94 (95%CI:2.09-4.13) and 4.48 (95%CI:2.17-9.27) respectively. Either father or mother having the positive family history of hypertension, the corresponding OR values appeared as 2.50 (95%CI:1.84-3.40), 1.61(95%CI:1.22-2.12) seen in mothers. However, when both father and mother having the family history of hypertention, the OR value was seen 2.82 (95%CI:1.76-4.51) in the mothers. Conclusion Family history appeared as a risk factor for hypertension. The number of first-degree relatives with positive family history showed a dose-response relationship to the occurrence of hypertension. Family history in both father or mother might further affect the incidence of hypertension. |
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