尤优,严双琴,黄锟,毛雷婧,周珊珊,葛星,郝加虎,朱鹏,陶芳标.妊娠意愿与孕中晚期妊娠相关焦虑关联的队列研究[J].中华流行病学杂志,2017,38(9):1179-1182 |
妊娠意愿与孕中晚期妊娠相关焦虑关联的队列研究 |
Pregnancy intention and pregnancy-related anxiety in the second and third trimester:a birth cohort study |
收稿日期:2017-01-17 出版日期:2017-09-09 |
DOI:10.3760/cma.j.issn.0254-6450.2017.09.007 |
中文关键词: 妊娠相关焦虑 妊娠意愿 队列研究 |
英文关键词: Pregnancy-related anxiety Pregnancy intention Cohort study |
基金项目:国家自然科学基金(81330068,81373012) |
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中文摘要: |
目的 探讨妊娠意愿与孕中、晚期妊娠相关焦虑关联及其强度。方法 在马鞍山优生优育队列(MABC)中,将孕周≤ 14周、符合纳入标准的3 474名孕妇纳入队列。在首次产检时收集孕妇的一般人口学信息,并在孕中期和孕晚期收集妊娠相关焦虑量表。采用logistic回归分析妊娠意愿对孕中期和孕晚期妊娠相关焦虑的影响。结果 最终3 083人纳入分析,意外妊娠检出率为15.00%(n=461)。孕中期和孕晚期妊娠相关焦虑检出率分别为29.13%(n=898)、30.36%(n=936)。控制潜在的混杂因素后,与有充分思想准备的孕妇相比,意外妊娠的孕妇孕中期出现妊娠相关焦虑的风险增加(OR=1.85,95%CI:1.44~2.38);孕晚期出现妊娠相关焦虑的风险也增加(OR=1.84,95%CI:1.44~2.35);顺其自然怀孕的孕妇在孕中、晚期未增加妊娠相关焦虑发生风险。结论 意外妊娠是孕中、晚期妊娠相关焦虑危险因素。 |
英文摘要: |
Objective To understand the association between pregnancy intention and pregnancy-related anxiety in the second and third trimester and its strength. Methods A prospective cohort study was conducted in Ma'anshan, Anhui province. A total of 3 474 eligible pregnant women within 14 weeks of gestation were recruited. The information about their demographic characteristics were collected in early pregnancy. The completed questionnaire of pregnancy-related anxiety were asked to return in the second and third trimester. Logistic regression analysis was conducted to evaluate the association between pregnancy intention and pregnancy-related anxiety in the second and third trimester. Results A total of 3 083 pregnant women were included in final analysis, The rate of unintentional pregnancy was 15.00% (n=461). The detection rates of pregnancy-related anxiety in the second and third trimester were 29.13% (n=898) and 30.36% (n=936). After controlling potential confounding factors, unintentional pregnancy increased the risk of pregnancy-related anxiety in the second trimester compared with intentional pregnancy (OR=1.85, 95%CI:1.44-2.38); The risk of pregnancy-related anxiety also increased in the third trimester (OR=1.84, 95%CI:1.44-2.35). Intentional pregnancy did not increase the risk of pregnancy-related anxiety in the second and third trimester. Conclusion The study results suggests that unintentional pregnancy could increase the risk of pregnancy-related anxiety in the second and third trimester. |
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