| 郭兰伟,张韶凯,刘曙正,杨福娜,吴越,郑黎阳,陈琼,曹小琴,孙喜斌,张建功.河南省城市地区低剂量螺旋CT肺癌筛查依从性及其影响因素分析[J].中华流行病学杂志,2020,41(7):1076-1080 |
| 河南省城市地区低剂量螺旋CT肺癌筛查依从性及其影响因素分析 |
| Compliance of lung cancer screening with low-dose computed tomography and influencing factors in urban area of Henan province |
| 收稿日期:2019-07-30 出版日期:2020-07-15 |
| DOI：10.3760/cma.j.cn112338-20190730-00564 |
| 中文关键词: 肿瘤，肺 筛查 依从性 |
| 英文关键词: Neoplasms,lung Screening Compliance |
| 基金项目:河南省科技攻关计划（192102310353）；国家重大公共卫生服务专项——城市癌症早诊早治项目 |
|
| 摘要点击次数: 3055 |
| 全文下载次数: 929 |
| 中文摘要: |
| 目的 评价2013-2017年河南省城市地区肺癌高危人群的低剂量螺旋CT（LDCT）筛查依从性并探索可能的影响因素。方法 采取整群抽样的方法，选取河南省40～74岁城市户籍居民进行癌症危险因素调查和肺癌风险评估，并对评估出的肺癌高危人群进行LDCT检查。采用χ2检验比较不同特征人群的LDCT筛查参与率差异，并采用Cochran-Armitage趋势检验对筛查参与率的时间趋势进行检验；采用多因素logistic回归模型分析LDCT筛查参与率的影响因素。结果 共纳入符合研究要求的肺癌高危人群35 672例，其中13 383例接受了LDCT检查，总体参与率为37.52%。LDCT筛查的参与率存在显著的地区和时间差异：最高和最低城市的参与率分别为38.47%和26.73%；2013-2014年的总体筛查参与率最低，为29.22%，2014-2015年最高，为43.30%（P<0.05），且随着筛查年份增加，筛查参与率逐渐增加（P<0.001）。多因素logistic回归分析显示，女性、45～69岁、具有初/高中文化程度、既往吸烟、正在饮酒或既往饮酒、不经常体育锻炼、有肺结核史、有慢性支气管炎史、有肺气肿史、有哮喘支气管扩张史和有肺癌家族史的人群更愿意接受LDCT检查（均P<0.05）。结论 河南省城市肺癌高危人群的LDCT筛查参与率仍不高。针对本研究识别出的特定高危人群采取相应的干预措施可能会在将来的肺癌筛查中提升LDCT检查的总体依从性。 |
| 英文摘要: |
| Objective To evaluate the compliance of low-dose computed tomography (LDCT) screening for high-risk groups of lung cancer and influencing factors in urban area of Henan province during 2013-2017. Methods Cluster sampling method was used to select the residents of 40-74 years old in Henan for cancer risk factor investigation and lung cancer risk assessment. Subjects with high risk of lung cancer received LDCT screening. The differences of LDCT receiving rates between groups were compared with χ2 tests, and the time trend of rates were tested with the Cochran-Armitage trend test. The potential factors correlating to the compliance of LDCT screening were identified with multivariate logistic regression models. Results Overall, 35 672 participants who met the inclusion criteria were included in this analysis, and 13 383 of them received LDCT screening, the receiving rate was 37.52%. The receiving rate varied greatly across cities, ranging from 38.47% to 26.73% (P<0.05). Moreover, the receiving rate varied greatly across periods, ranging from 29.22% during 2013-2014 to 43.30% during 2014-2015, and the receiving rate increases gradually as the screening year increases (P<0.001). The multivariate logistic regression analyses showed that:being female, age 45-69 years, with education level of junior high school/high school, previous smoking, drinking or previous drinking, infrequent physical exercise, history of tuberculosis, history of chronic bronchitis, history of emphysema, history of asthma bronchiectasis and family history of lung cancer were positive factors for receiving LDCT screening (All P<0.05). Conclusions The overall compliance of LDCT screening in high-risk population of lung cancer was still not high in urban area of Henan. Implementation of effective interventions targeting the specific high-risk populations might improve the overall compliance of LDCT screening in the future. |
|
查看全文
Html全文
查看/发表评论 下载PDF阅读器 |
|
| 关闭 |
|
|
|
