| 刘璇,张一方,湛永乐,岳和欣,桂路婷,边峰,魏文强,江宇.食管癌筛查队列操作流程与建设标准方案探讨[J].中华流行病学杂志,2021,42(8):1504-1508 |
| 食管癌筛查队列操作流程与建设标准方案探讨 |
| Study on the operation process and construction standard of an esophageal cancer screening cohort study |
| 收稿日期:2020-09-30 出版日期:2021-08-19 |
| DOI：10.3760/cma.j.cn112338-20200930-01215 |
| 中文关键词: 食管癌 癌症筛查 队列建设 技术规范 |
| 英文关键词: Esophageal cancer Cancer screening Cohort construction Technical specification |
| 基金项目:中国医学科学院医学与健康科技创新工程（2019-I2M-2-004） |
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| 中文摘要: |
| 癌症防治工作的重点在于一级预防和二级预防，通过健康教育引起人们对疾病的重视、自觉改变不良行为习惯、主动参加定期体检是防治癌症性价比最高的措施之一。食管癌作为我国疾病负担较重的恶性肿瘤之一，定期筛查和早诊早治是该病防治工作的重点。而队列研究有助于了解食管癌的自然史和危险因素、识别食管癌高危人群。本研究拟从危险因素调查、疾病监测、生物样本信息搜集等方面对食管癌多维动态随访共享队列的建设规范进行探讨，为今后建立规范统一的食管癌筛查队列研究操作流程和建设标准提供参考。 |
| 英文摘要: |
| One of the most cost-effective measures in cancer prevention on cancer is to advocate to be aware of the disease, consciously changing negative behaviors, and taking the initiative to participate in regular physical checkup programs. Esophageal cancer is one of the malignant tumors accompanied by a heavy disease burden in China. Routine screening, early diagnosis, and treatment are the critical points of preventing and treating the disease. Cohort studies help understand the natural history and risk factors of esophageal cancer and identify high-risk groups of the disease. This paper intends to discuss the construction specifications of the multi-dimensional dynamic follow-up shared cohort for esophageal cancer by studying the risk factors, monitoring, and collecting biological sample information, providing references for developing a standardized and unified screening cohort research procedure, and necessary standards on esophageal cancer in the future. |
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