文章摘要
胡海洋,陈禹衡,周莹,张之,卢静,刘晓燕,陈莉萍,傅更锋.江苏省男男性行为人群HIV新发感染及影响因素分析[J].中华流行病学杂志,2021,42(11):1989-1993
江苏省男男性行为人群HIV新发感染及影响因素分析
Recent HIV infection and associated factors among men who have sex with men in Jiangsu province
收稿日期:2021-06-01  出版日期:2021-11-20
DOI:10.3760/cma.j.cn112338-20210601-00441
中文关键词: 男男性行为人群;艾滋病病毒;限制性抗原亲和力酶联免疫法;新发感染
英文关键词: Men who have sex with men;HIV;Limiting-antigen avidity enzyme immunoassay;Recent infections
基金项目:江苏省卫生健康委员会科研课题(Z2018039)
作者单位E-mail
胡海洋 江苏省疾病预防控制中心性病艾滋病防制所, 南京 210009  
陈禹衡 江苏省疾病预防控制中心性病艾滋病防制所, 南京 210009  
周莹 江苏省疾病预防控制中心性病艾滋病防制所, 南京 210009  
张之 江苏省疾病预防控制中心性病艾滋病防制所, 南京 210009  
卢静 江苏省疾病预防控制中心性病艾滋病防制所, 南京 210009  
刘晓燕 江苏省疾病预防控制中心性病艾滋病防制所, 南京 210009  
陈莉萍 江苏省疾病预防控制中心性病艾滋病防制所, 南京 210009  
傅更锋 江苏省疾病预防控制中心性病艾滋病防制所, 南京 210009 fugf@jscdc.cn 
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中文摘要:
      目的 分析江苏省MSM的HIV新发感染及影响因素。方法 根据2019年全国艾滋病哨点监测方案,2019年4-7月在江苏省13个城市招募MSM,进行问卷调查及实验室检测,应用限制性抗原亲和力酶联免疫法(LAg-Avidity EIA)检测HIV新发感染者,根据中国CDC推荐的基于亲和力方法的计算公式及参数计算新发感染率;采用多因素logistic回归模型分析HIV新发感染的影响因素。结果 研究对象MSM 4 469人,HIV新发感染率为4.5%(95%CI:3.4%~5.5%)。多因素logistic分析结果显示,相比于≥ 40岁年龄组、招募途径来自MSM活动场所、艾滋病知识知晓、最近6个月未发生无保护肛交、无梅毒现症感染,18~24岁年龄组(aOR=2.083,95%CI:1.087~3.990)、招募途径来自VCT门诊(aOR=2.125,95%CI:1.175~3.843)、艾滋病知识不知晓(aOR=2.456,95%CI:1.109~5.437)、最近6个月发生无保护性肛交(aOR=3.553,95%CI:2.143~5.889)、梅毒现症感染(aOR=2.414,95%CI:1.033~5.462)的HIV新发感染风险较高。结论 江苏省MSM人群HIV新发感染率较高。MSM的艾滋病预防控制,需加强健康教育、推广使用安全套和促进HIV/梅毒筛查工作。
英文摘要:
      Objective To understand the incidence of HIV infections and associated factors among men who have sex with men (MSM) in Jiangsu province. Methods Based on national AIDS sentinel surveillance in 2019, MSM from 13 cities in Jiangsu were recruited for questionnaire interview and laboratory testing during April to July, 2019. Seropositive samples were tested with Limiting-antigen avidity enzyme immunoassay to detect recent HIV infections. The incidence of HIV infection in MSM were calculated according to the formula and parameters from China CDC. Multivariable logistic regression analysis was used to identify factors associated with recent infection of HIV. Results A total of 4 469 MSM were subjects and the incidence of HIV infection were 4.5% (95%CI:3.4%-5.5%).Multivariate logistic regression analysis results showed that compared with these aged ≥ 40 years, recruitment ways from MSM venues, awareness of AIDS knowledge, non-unprotected anal sex in the past 6 months and non-syphilis infection, those who aged 18-24 years (aOR=2.083,95%CI:1.087-3.990), recruitment ways from VCT clinics (aOR=2.125,95%CI:1.175-3.843), unawareness of AIDS knowledge (aOR=2.456,95%CI:1.109-5.437), unprotected anal sex in the past 6 months (aOR=3.553,95%CI:2.143-5.889) and syphilis infection (aOR=2.414,95%CI:1.033-5.462) were higher risk of HIV infection. Conclusion The new infection rates of HIV were high in MSM in Jiangsu province. Health education, condom use and HIV/syphilis screening promotions should therefore be top priority in the prevention and control of HIV infection in MSM.
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