文章摘要
魏玥,林进龙,陈功,裴丽君.中国65岁及以上老年人睡眠时长与其认知障碍风险的关联研究[J].中华流行病学杂志,2021,42(12):2138-2142
中国65岁及以上老年人睡眠时长与其认知障碍风险的关联研究
Association between sleep duration and cognitive impairment in Chinese people aged 65 years and older
收稿日期:2020-11-06  出版日期:2021-12-16
DOI:10.3760/cma.j.cn112338-20201106-01313
中文关键词: 认知障碍;睡眠时长;老年人
英文关键词: Cognitive impairment;Sleep duration;Older adults
基金项目:国家自然科学基金(41871360);国家重点研发计划(2018YFC2000603)
作者单位E-mail
魏玥 北京大学人口研究所/北京大学中国人口与健康发展研究中心 100871  
林进龙 北京大学人口研究所/北京大学中国人口与健康发展研究中心 100871  
陈功 北京大学人口研究所/北京大学中国人口与健康发展研究中心 100871  
裴丽君 北京大学人口研究所/北京大学中国人口与健康发展研究中心 100871 peilj@pku.edu.cn 
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中文摘要:
      目的 探讨我国老年人睡眠时长与认知障碍患病风险的关联。方法 数据来源于2018年中国老年健康影响因素跟踪调查(CLHLS),按照中文版简易智力状态检查测试量表(CMMSE)将7 111例≥ 65岁老年人分为认知障碍组和认知正常组,使用多因素logistic回归模型分析睡眠时长与认知障碍患病风险之间的关联。结果 研究对象的CMMSE得分随睡眠时长呈倒"U"形分布;调整了人口学、社会经济因素、生活方式和健康状况后,与睡眠时长为7 h的老年人相比,睡眠时长为8 h和≥ 9 h的老年人患认知障碍的OR值分别为1.21(95%CI:0.90~1.64)和1.41(95%CI1.06~1.86),趋势检验显示,随着睡眠时间延长(>7 h)老年人患认知障碍的风险增加,且存在剂量反应关系(趋势性P=0.017),而睡眠时间<7 h的老年人与认知障碍发生风险无关。结论 我国≥ 65岁老年人的睡眠时间过长与其认知障碍患病风险存在关联。
英文摘要:
      Objective To explore the association between sleep duration and cognitive impairment in older adults in China. Methods The data was from 2018 Chinese Longitudinal Healthy Longevity Survey (CLHLS). According to the Chinese version of Mini-mental State Examination (CMMSE), 7 111 subjects aged 65 and above were divided into cognitive impaired group and cognitive intact group. Multiple logistic regression analysis was conducted to investigate the association between sleep duration and the risk of cognitive impairment after adjusting the potential confounding factors. Result The score of cognitive function showed an inverted U-shape distribution with sleep duration. After adjusting for demographic, socioeconomic factors, lifestyle and health status, the OR were 1.21(95%CI: 0.90-1.64) and 1.41(95%CI: 1.06-1.86) in groups that sleep 8 h and ≥ 9 h per day respectively, compared with sleep 7 h group. Trend test showed that the risk of cognitive impairment in the elderly increased with the extension of sleep duration, and there was a dose-response relationship (trend P=0.017), while no association was observed between short sleep duration (<7 h) and cognitive function. Conclusion Longer sleep duration was found to be associated with higher risk of cognitive impairment in the Chinese aged 65 years and older.
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