文章摘要
韩耀风,杨玉婷,方亚.我国农村老年人抑郁倾向与认知功能变化轨迹关系研究[J].中华流行病学杂志,2022,43(9):1491-1496
我国农村老年人抑郁倾向与认知功能变化轨迹关系研究
Association between depression tendency and cognitive trajectory in the elderly in rural area in China
收稿日期:2022-04-15  出版日期:2022-09-09
DOI:10.3760/cma.j.cn112338-20220415-00302
中文关键词: 抑郁倾向;认知功能变化轨迹;老年人;农村
英文关键词: Depression tendency;Cognitive trajectory;The elderly;Rural area
基金项目:福建省自然科学基金(2019J01038)
作者单位E-mail
韩耀风 厦门大学公共卫生学院, 厦门 361102
卫生技术评估福建省高校重点实验室, 厦门 361102 
 
杨玉婷 厦门大学公共卫生学院, 厦门 361102
卫生技术评估福建省高校重点实验室, 厦门 361102 
 
方亚 厦门大学公共卫生学院, 厦门 361102
卫生技术评估福建省高校重点实验室, 厦门 361102 
fangya@xmu.edu.cn 
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中文摘要:
      目的 探索我国农村老年人抑郁倾向与认知功能变化轨迹的关系。方法 基于中国老年健康影响因素跟踪调查(CLHLS)中2011-2018年农村≥65岁老年人的数据,分别构建无条件和条件潜变量增长曲线模型,分析我国农村老年人简易精神状态评价量表(MMSE)得分变化轨迹及与抑郁倾向的关系。结果 最终纳入了1 788名2011/2012年开始调查的农村老年人,其中有抑郁倾向者占19.1%;有、无抑郁倾向者基线MMSE得分别为26.62±3.54和27.59±3.17。无条件和条件潜变量增长曲线模型结果显示:MMSE得分下降率为0.52分(P<0.05);纳入协变量前后,有抑郁倾向者MMSE初始得分比无抑郁倾向者分别低0.84分(P<0.05)和0.81分(P<0.05),有抑郁倾向者MMSE得分下降速度比无抑郁倾向者分别慢0.33分(P<0.05)和0.40分(P<0.05)。结论 我国农村老年人抑郁倾向与认知功能变化轨迹有关,有抑郁倾向者处于更低水平轨迹,提示应积极关注我国农村老年人的心理健康并及时干预,以延缓或防止老年痴呆的发生发展。
英文摘要:
      Objective To explore cognitive trajectory and its association with depression tendency in the elderly in rural area in China.Methods Based on the data of the rural elderly aged ≥ 65 years in the Chinese Longitudinal Healthy Longevity Survey (CLHLS) from 2011 to 2018,unconditional and conditional latent variable growth curve models were constructed to analyze the mini-mental state examination (MMSE) score trajectory and its association with depression tendency in the elderly.Results A total of 1 788 elderly persons were included,and 19.1% of them had a depression tendency.The average MMSE score of those with and without a depression tendency at baseline survey were 26.62±3.54 and 27.59±3.17 respectively.The rate of MMSE score decline was 0.52 points (P<0.05).Before and after controlling covariates,the initial score was 0.84 points lower (P<0.05) and 0.81 points lower (P<0.05) in those with depressive tendency than in those without depressive tendency respectively,furthermore,the decline rate of MMSE score was 0.33 points lower (P<0.05) and 0.40 points lower (P<0.05) in those with depressive tendency than in those without respectively.Conclusions The depression tendency in the elderly in rural area in China was associated with the cognitive function change trajectory,with those with depression tendency had lower-level trajectory.Attention should be paid to the mental health of the elderly in rural area to prevent dementia and slow its development.
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