| 房玥晖,何宇纳,连怡遥,王增武,殷鹏,赵振平,亢玉婷,方柯红,丁钢强.中国出血性卒中和高血压性心脏病归因于饮酒的疾病负担研究[J].中华流行病学杂志,2023,44(3):393-400 |
| 中国出血性卒中和高血压性心脏病归因于饮酒的疾病负担研究 |
| Burden of hemorrhagic stroke and hypertensive heart disease attributed to alcohol consumption in China |
| 收稿日期:2022-06-10 出版日期:2023-03-14 |
| DOI：10.3760/cma.j.cn112338-20220610-00516 |
| 中文关键词: 饮酒 出血性卒中 高血压性心脏病 疾病负担 地理分布 |
| 英文关键词: Alcohol consumption Hemorrhagic stroke Hypertensive heart disease Burden of disease Geographical distribution |
| 基金项目:国家重点研发计划（2018YFC1315303） |
| 作者 | 单位 | E-mail | | 房玥晖 | 中国疾病预防控制中心营养与健康所, 北京 100050
国家卫健委微量元素与营养重点实验室, 北京 100050 | | | 何宇纳 | 中国疾病预防控制中心营养与健康所, 北京 100050
国家卫健委微量元素与营养重点实验室, 北京 100050 | | | 连怡遥 | 中国疾病预防控制中心营养与健康所, 北京 100050
国家卫健委微量元素与营养重点实验室, 北京 100050 | | | 王增武 | 中国医学科学院阜外医院国家心血管病防治中心社区防治部, 北京 102308 | | | 殷鹏 | 中国疾病预防控制中心慢性非传染性疾病预防控制中心, 北京 100050 | | | 赵振平 | 中国疾病预防控制中心慢性非传染性疾病预防控制中心, 北京 100050 | | | 亢玉婷 | 北京医院国家老年疾病临床医学研究中心办公室/国家老年医学中心/中国医学科学院老年医学研究所, 北京 100730 | | | 方柯红 | 杭州市疾病预防控制中心健康危险因素监测所, 杭州 310021 | | | 丁钢强 | 中国疾病预防控制中心营养与健康所, 北京 100050
国家卫健委微量元素与营养重点实验室, 北京 100050 | dinggq@chinacdc.cn |
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| 中文摘要: |
| 目的 描述我国2005-2018年各省份≥20岁成年人饮酒行为及变化趋势，分析各省份出血性卒中和高血压性心脏病死亡归因于饮酒的负担。方法 利用中国居民营养与健康状况监测、中国慢性病及危险因素监测、中国成人慢性病与营养监测和中国高血压调查数据，采用克里金插值结合局部加权回归，估计2005-2018年我国居民饮酒暴露水平；采用2019全球疾病负担研究方法以及中国死因监测数据，计算我国各省份不同性别≥20岁人群饮酒对出血性卒中和高血压性心脏病死亡的人群归因分值（PAF）和归因死亡人数，利用2010年中国人口普查数据计算归因标化死亡率。结果 2005和2018年男性过去12个月饮酒率分别为58.7%（95%CI：57.8%~59.5%）和58.4%（95%CI：57.6%~59.3%），女性过去12个月饮酒率分别为17.0%（95%CI：16.6%~17.4%）和18.7%（95%CI：18.1%~19.3%），男性饮酒者日均酒精摄入量分别为24.6（95%CI：23.8~25.3）g和27.7（95%CI：26.8~28.7）g，女性饮酒者日均酒精摄入量分别为6.3（95%CI：6.0~6.5）g和5.3（95%CI：5.0~5.6）g，东部地区高于西部，西北地区饮酒暴露水平最低。2005-2018年出血性卒中死亡归因于饮酒的PAF从5.5%升至6.8%，归因死亡人数从5.02万升至5.91万；高血压性心脏病死亡归因于饮酒的PAF从7.0%升至7.7%，归因死亡人数从1.52万升至2.93万。各省份饮酒导致的高血压性心脏病和出血性卒中的PAF均为男性远高于女性，中、东部地区高于西部，西北地区最低，2018年归因于饮酒的出血性卒中和高血压性心脏病标化死亡率分别为4.58/10万和2.11/10万。结论 我国男性居民饮酒率和饮酒者日均酒精摄入量均较高，特别是东部地区，女性饮酒行为则较少，应采取区域性措施降低男性居民和饮酒者日均酒精摄入量，以减少饮酒导致的健康问题。 |
| 英文摘要: |
| Objective To describe the prevalence of alcohol consumption and the burden of hemorrhagic stroke and hypertensive heart disease attributed to alcohol consumption in adults aged ≥ 20 years in 31 provinces in China from 2005 to 2018. Methods Data from several national representative surveys was used to estimate provincial alcohol exposure level of adults aged ≥ 20 years from 2005 to 2018 by using kriging interpolation and locally weighted regression methods. Global disease burden research method and data, and China's death cause surveillance data were used to calculate the population attributable fraction (PAF) of hemorrhagic stroke and hypertensive heart disease and the deaths due to alcohol consumption in men and women aged ≥ 20 years in 31 provinces in China. China census data of 2010 were used to calculate the attributable standardized mortality rate. Results In 2005 and 2018, the prevalence of alcohol consumption was 58.7% (95%CI:57.8%-59.5%) and 58.4% (95%CI:57.6%-59.3%), respectively, in men and 17.0% (95%CI:16.6%-17.4%) and 18.7% (95%CI:18.1%-19.3%), respectively, in women. The daily alcohol intake was 24.6 (95%CI:23.8-25.3) g and 27.7 (95%CI:26.8-28.7) g, respectively, in men and 6.3 (95%CI:6.0-6.5) g and 5.3 (95%CI:5.0-5.6) g, respectively, in women. Alcohol exposure level was higher in the provinces in central and eastern China than in western provinces. The lowest exposure level was found in northwestern provinces. From 2005 to 2018, the PAF of hemorrhagic stroke death due to alcohol consumption increased from 5.5% to 6.8%, the attributable deaths increased from 50 200 to 59 100, while the PAF of hypertensive heart disease death due to alcohol consumption increased from 7.0% to 7.7%, the attributable deaths increased from 15 200 to 29 300. The PAF of hypertensive heart disease and hemorrhagic stroke was higher in men than in women, and in central and eastern provinces than in western provinces. In 2018, the standardized mortality rates of hemorrhagic stroke and hypertensive heart disease attributed to alcohol consumption were 4.58/100 000 and 2.11/100 000, respectively. Conclusions The prevalence of alcohol consumption in men and daily alcohol intake of drinkers were relatively high in China, especially in eastern provinces. Alcohol exposure level was lower in women than in men. Regional measures should be taken to reduce the alcohol intakes in men and current drinkers in order to reduce the health problems caused by alcohol consumption. |
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