文章摘要
李珂,张海东,简文秀,孙晓敏,赵磊,汪海静,尕藏卓玛,王彦香,许志华,王友发,彭雯.青海省藏族牧民肥胖流行状况及其与饮食模式关系的队列研究[J].中华流行病学杂志,2023,44(8):1257-1263
青海省藏族牧民肥胖流行状况及其与饮食模式关系的队列研究
Prevalence of obesity and its association with dietary patterns:a cohort study among Tibetan pastoralists in Qinghai Province
收稿日期:2022-12-25  出版日期:2023-08-18
DOI:10.3760/cma.j.cn112338-20221225-01082
中文关键词: 肥胖  中心性肥胖  患病率  饮食模式  危险因素  保护因素
英文关键词: Obesity  Central obesity  Prevalence  Dietary pattern  Risk factors  Protective factors
基金项目:国家自然科学基金(82103846);青海省重点研发与转化计划(2023-QY-204);青海省重大科技专项(2021-NK-A3);中国营养学会营养科普与传播研究基金(CNS-SCP2020-40)
作者单位E-mail
李珂 西安交通大学全球健康研究院公共卫生学院, 西安 710049  
张海东 青海省格尔木市疾病预防控制中心, 格尔木 816000  
简文秀 青海大学医学部营养健康促进中心公共卫生系, 西宁 810008  
孙晓敏 西安交通大学全球健康研究院公共卫生学院, 西安 710049
西安交通大学国际肥胖与代谢性疾病研究中心, 西安 710049 
 
赵磊 青海大学医学部营养健康促进中心公共卫生系, 西宁 810008  
汪海静 青海大学医学部营养健康促进中心公共卫生系, 西宁 810008  
尕藏卓玛 青海大学医学部营养健康促进中心公共卫生系, 西宁 810008  
王彦香 青海大学医学部营养健康促进中心公共卫生系, 西宁 810008  
许志华 青海省疾病预防控制中心慢性非传染病预防控制所, 西宁 810007  
王友发 西安交通大学全球健康研究院公共卫生学院, 西安 710049
西安交通大学国际肥胖与代谢性疾病研究中心, 西安 710049 
youfawang@gmail.com 
彭雯 青海大学医学部营养健康促进中心公共卫生系, 西宁 810008
青海省糖脂代谢疾病防控中医药重点实验室, 西宁 810008 
wen.peng2014@foxmail.com 
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中文摘要:
      目的 探索青海省城镇化转型中藏族牧民成年人肥胖的流行状况及其与饮食模式的关系。方法 采用开放队列设计,2018年基线入组1 003人,2022年随访599人,新入组1 012人。共纳入 ≥ 18岁成年人1 913人,对其开展问卷调查和健康检查。使用因子分析法识别饮食模式,用混合效应模型分析饮食模式与肥胖关系。结果 2018-2022年超重、肥胖和中心性肥胖患病率分别为27.6%、33.8%和54.6%,肥胖和中心性肥胖年龄性别标化患病率均上升。共识别3种饮食模式:现代饮食模式(常食用猪肉、家禽肉类、加工肉类、新鲜水果、含糖饮料、咸味零食等)、城镇饮食模式(常食用精制碳水化合物、牛羊肉、蔬菜和鲜蛋类等)、牧区饮食模式(常食用糌粑、藏式奶酪、酥油茶/奶茶和乳制品等)。校正人口学特征、社会经济状况及生活行为方式后,相比城镇饮食模式得分T1组,T3组超重和超重/肥胖风险显著增加(超重:OR=2.09,95%CI:1.10~3.95;超重/肥胖:OR=1.23,95%CI:1.00~1.51),而牧区饮食模式得分T3组超重、肥胖、超重/肥胖和中心性肥胖的风险降低(超重:OR=0.45,95%CI:0.24~0.84;肥胖:OR=0.81,95%CI:0.69~0.95;超重/肥胖:OR=0.75,95%CI:0.61~0.91;中心性肥胖:OR=0.58,95%CI:0.38~0.89)。结论 城镇化转型中藏族牧民肥胖和中心性肥胖高发。城镇饮食模式是超重、超重/肥胖的危险因素,牧区饮食模式是超重、肥胖、超重/肥胖和中心性肥胖的保护因素。需制定针对性干预措施,提升健康水平。
英文摘要:
      Objectives To explore obesity prevalence and its association with dietary patterns among Tibetan pastoralists during the urbanization transition in Qinghai Province. Methods Using an open cohort study design, 1 003 subjects were enrolled at baseline in 2018, 599 were followed up, and 1 012 were newly recruited in 2022. A total of 1 913 adults over 18 years were included in the study, and a questionnaire survey and health examination were conducted. Factor analysis was used to identify dietary patterns, and a mixed-effects model was used to analyze the association between dietary patterns and obesity. Results From 2018 to 2022, the prevalence rates of overweight, obesity, and central obesity were 27.6%, 33.8%, and 54.6%, respectively. Age-sex-standardized prevalence of obesity and central obesity increased. Three dietary patterns were identified:the modern pattern was characterized by frequent consumption of pork, poultry, processed meat, fresh fruits, sugary drinks, salty snacks, etcetera; the urban pattern was characterized by frequent consumption of refined carbohydrates, beef and mutton, vegetables and eggs, etcetera; and pastoral pattern featured frequent consumption of tsamba, Tibetan cheese, buttered/milk tea, and whole-fat dairy products. After adjusting for demographic characteristics, socioeconomic status, and lifestyle factors, compared with the T1, subjects in the T3 of urban pattern scores were more likely to be overweight (OR=2.09, 95%CI:1.10-3.95) and overweight/obese (OR=1.23, 95%CI:1.00-1.51), whereas those in the T3 of pastoral pattern scores had a lower risk of overweight (OR=0.45, 95%CI:0.24-0.84), obesity (OR=0.81, 95%CI:0.69-0.95), overweight/obesity (OR=0.75, 95%CI:0.61-0.91) and central obesity (OR=0.58, 95%CI:0.38-0.89). Conclusions Prevalence of obesity and central obesity was high among Tibetan pastoralists during the urbanization transition. Urban dietary pattern was a risk factor for overweight and overweight/obesity, whereas pastoral dietary pattern was a protective factor for overweight, obesity, overweight/obesity, and central obesity. Tailored interventions are needed to improve local people's health.
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