| 丁贤彬,焦艳,唐佳诗,吕晓燕,丁睿,陈莉玲.重庆市2012-2023年慢性肾脏病死亡疾病负担及趋势变化研究[J].中华流行病学杂志,2025,46(1):43-49 |
| 重庆市2012-2023年慢性肾脏病死亡疾病负担及趋势变化研究 |
| Change trend of disease burden of chronic kidney disease mortality in Chongqing, 2012-2023 |
| 收稿日期:2024-05-18 出版日期:2025-01-11 |
| DOI：10.3760/cma.j.cn112338-20240518-00286 |
| 中文关键词: 慢性肾脏病 死亡率 早死损失寿命年 疾病负担 |
| 英文关键词: Chronic kidney disease Mortality Years of life lost Disease burden |
| 基金项目:重庆市科卫联合医学科研项目（2024ZDXM017）；重庆第一批公共卫生重点学科（渝卫办发〔2022〕72号） |
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| 中文摘要: |
| 目的 分析重庆市慢性肾脏病（CKD）死亡疾病负担及趋势变化，为开展有针对性的干预提供建议。方法 利用2012-2023年重庆市死因监测数据中根本死因为《国际疾病分类》第十版的CKD编码，采用SPSS 26.0软件统计分析死亡率、标化死亡率、年龄别死亡率、早死损失寿命年（YLL）率和构成比，死亡率的比较采用χ2检验，率的趋势变化采用平均年变化百分比（AAPC）表示。结果 2012年重庆市CKD死亡率和标化死亡率分别为7.94/10万和4.63/10万，2023年CKD死亡率和标化死亡率分别为6.70/10万和2.79/10万，死亡率变化趋势差异无统计学意义（AAPC=-0.79%，t=-1.60，P=0.273），标化死亡率以年均3.59%下降（t=-3.98，P=0.003）。仅2014年和2022年男性CKD死亡率高于女性，差异有统计学意义（均P<0.05）。男性和女性CKD标化死亡率分别以年均3.17%和4.11%下降，变化趋势差异有统计学意义（均P<0.05）。2016年及以后城市地区CKD死亡率高于农村地区，差异有统计学意义（均P<0.05）。城市地区CKD死亡率和标化死亡率总体均保持相对平稳的水平，而农村地区CKD死亡率和标化死亡率总体分别以年均2.21%和4.90%下降，变化趋势差异有统计学意义（均P<0.05）。高血压导致的CKD构成比呈下降趋势，糖尿病和其他原因导致的CKD构成比呈上升趋势。2012-2023年CKD标化YLL率以年均2.83%下降，变化趋势差异有统计学意义（P=0.011）。结论 2012-2023年重庆市CKD标化死亡率和标化YLL率呈下降的趋势，男性和城市居民是CKD应重点关注的人群。 |
| 英文摘要: |
| Objective To analyze change trend of disease burden of chronic kidney disease (CKD) mortality between 2012 and 2023 in Chongqing, and provide suggestion for CKD prevention. Methods The mortality data of CKD were collected from Chongqing death registration between 2012 and 2023 according to International Classification of Diseases 10th. The data were analyzed to calculate mortality rate, standardized mortality rate, age specific mortality rate, and the rate of years of life lost (YLL) and proportion by using software SPSS 26.0. The mortality rate of CKD between men and women, urban area and rural area were compared by χ2 test. The change trend was described by average annual percent of change (AAPC). Results The mortality rate and standardized mortality rate of CKD were 7.94/100 000 and 4.63/100 000 respectively in 2012 and 6.70/100 000 and 2.79/100 000 respectively in 2023 in Chongqing. The difference in change of CKD mortality rate was not significant (AAPC=-0.79%, t=-1.60, P=0.273). However, the standardized mortality rate of CKD decreased by 3.59% (t=-3.98, P=0.003) from 2012 to 2023. The mortality rate of CKD was higher in men than in women in 2014 and 2022, the differences were significant (all P<0.05). The standardized mortality rate of CKD in men and women decreased by 3.17% and 4.11% respectively between 2012 and 2023, the difference was significant (all P<0.05). The mortality rate of CKD had been higher in urban area than in rural area since 2016 (all P<0.05). During this period, the mortality rate and standardized mortality rate of CKD in urban area remained stable, but the mortality rate and standardized mortality rate of CKD in rural area showed average annual decreases of 2.21% and 4.90%, the differences were significant (all P<0.05). The proportion of CKD due to hypertension decreased, but the proportion of CKD due to diabetes and other causes increased. The rate of age standardized YLL of CKD showed an average annual decrease of 2.83%, the differences were significant (P=0.011). Conclusions The standardized mortality rate and age standardized YLL of CKD decreased from 2012 to 2023 in Chongqing. Men, urban residents and the elderly are key populations in CKD prevention. |
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