| 许锐恒,耿贯一.天津市肺癌与吸烟关系的病例对照研究[J].Chinese journal of Epidemiology,1983,4(4):193-197 |
| 天津市肺癌与吸烟关系的病例对照研究 |
| A Case-Control Study of the Relationship Between Smoking and Lung Cancer in Tianjin |
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| Abstract: |
| 我们于1981年3月至10月在天津市六所大医院里进行了肺癌的病例对照研究,着重了解吸烟与肺癌的联系。调查了肺癌病例135人(男99,女36)、对照病人135人。病例与对照均为住院病人,90%的肺癌病例有病理学诊断依据。病例与对照作年龄、性别、民族、居住地配对。病例组与对照组的吸烟习惯有显著差异。吸烟者患肺癌的相对危险性男性为6,女性为4,两者的99%可信限均大于1。男女性均可见吸烟量与相对危险性之间有显著的剂量反应关系,其回归系数的95%可信限都不包括零。开始吸烟至发现肺癌的时间(潜隐期)的分布为正态分布,其均数为30年。 |
| English Abstract: |
| A retrospective case-control study of lung cancer was carried out in six large hospitals in Tianjin during Marclx-October, 1981, taking particular note of the relationship between smoking and lung cancer. One hundred and thirty-five patients with lung cancer(99 males and 36 females) and 135 controls were interviewed. Both cases and controls were inpatients. 90% of the cases were diagnosed pathologically. Caes and controls were matched by age, sex, race and residence. There is a significant difference in smoking habit between the two groups.The relative risk for male smoker is 6, for female is 4, both 99% confidence interval are larger than 1, A significant dose-response relationship between cigarette consumption and relative risk is found in both sexes, the 95% confidence intervals for regression coefficients don't include zero. The distribution of the latency periods from smoking to the detection of lung cancer is shown to be a normal one, it's arithraatic mean is 30 years. |
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