范宗华,劳伟宁,刘力克.人流感与猪流感关系的监测[J].Chinese journal of Epidemiology,1984,5(3):150-153 |
人流感与猪流感关系的监测 |
Surveillance of the Relationship of Influenza Infection Between Humans and Pigs |
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Abstract: |
作者于1982年4月和1983年5月在成都地区采集了336份人血清和607份猪血清。以Hsw1N1、H1N1、H2N2、H3N2和B流感病毒为抗原,用血抑试验检测其抗体,血抑阳性猪血清用单扩溶血试验复核结果表明,凡能感染人的流感病毒均能感染猪,猪血清和人血清中血抑抗体阳性率的增长呈平行关系。 此外,在22份猪血清中发现了B流感病毒的血抑抗体,阳性率为3.6%。经单扩溶血试验复核,其阳性率为72.7%。其中,4份猪血清与B病毒进行了中和试验,3份有中和B病毒的能力,猪血清中甲2型血抑抗体阳性率为78.3%,几何平均滴度为42.5,经单扩溶血试验复核,其阳性率为48.7%。血清学方面的事实证明B型流感病毒能感染猪,甲2型流感病毒近年来在猪群中曾广泛流行,並讨论了这些发现。 |
English Abstract: |
There were 336 human serum specimens and 607 pig serum specimens collected in April 1982 and may 1983 in Chengdu area. Antibodies to influenza Viruses were detected with antigens including Hsw1N1,H1N1,H2N2,two strains of H3N2 and influenza B virus by the heamagglutination (HI) test. All HI positive specimens of pig sera were retested by the single radial hemolysis (S.R.H.) test. The results showed that the pigs could be infected by all kinds of influenza virus which could infect humans and that the HI positive rate in pig sera ran parellel with that in human sera. Furthermore HI antibodies to influenza B virus were found in 22 pig sera and the positive rate was 3.6%. The positive rate became 72.7% when retested by S.R.H.test. When four pig sera with HI positive were run in virusneutralization (VN) tests with B virus,three showed the ability to neutralize B virus.In pig sera the H2N2, HI positive rate was 78.3% and the geometric mean of HI antibody titers was 42.5. The positive rate became 48.7%when retested by S, R, H, test.The facts have proved serologically that the pigs can be infected by influenza B virus and that H2N2 type virus has been prevalent in pigs in the past few years.Some other findings were also discussed. |
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